Chapter 12, Problem 2CSL

Summary Introduction

To explain:

The reason for more time taken in the reestablishment of an innervation process than in circulation.

Concept introduction:

If axon due to an injury gets separated from its cell body, its myelin sheath at the distal end gets deteriorated. The cell debris and cell body of these deteriorated cells are removed by macrophages. The sprout neuroglia present at the proximal end then secretes nerve growth factors that influence the sprouts to develop the injured axon. The Schwann cells then start surrounding the new axons for its regeneration.