To discuss:
That how researchers might use a GFP-labeled protein to study cancer.
Introduction:
Any mutation or alteration in the DNA sequence causes mutations. Cancer is a disease that is caused due to mutation in a cell that results in the abnormal or uncontrolled cell division. GFP or green fluorescent protein is a protein which is bioluminescent and is found in jellyfish. The fluorescent proteins are used as molecular tags.

Explanation of Solution
When the uncontrolled growth of cell or tumor spreads to other sites inside the body by metastasis, it is called as malignant tumor. When a malignant tumor spreads to other parts it starts forming new secondary tumor at new site which contains similar cells like that of original tumors.
The fluorescent proteins of GFP are used as a tag to label the cancerous cells. By this, when tagged cancerous cells will spread to other places in the body, its path could be tracked.
Thus by tagging cancer cells with GFP, their location and distribution can be determined.
Proteins which are GFP labeled are very useful in studying cancer.
Want to see more full solutions like this?
Chapter 12 Solutions
BIOL 107 LAB PKG W/LAB SG +ACCESS >IC<
- 1. Match each vocabulary term to its best descriptor A. affinity B. efficacy C. inert D. mimic E. how drugs move through body F. how drugs bind Kd Bmax Agonist Antagonist Pharmacokinetics Pharmacodynamicsarrow_forward50 mg dose of a drug is given orally to a patient. The bioavailability of the drug is 0.2. What is the volume of distribution of the drug if the plasma concentration is 1 mg/L? Be sure to provide units.arrow_forwardDetermine Kd and Bmax from the following Scatchard plot. Make sure to include units.arrow_forward
- Choose a catecholamine neurotransmitter and describe/draw the components of the synapse important for its signaling including synthesis, packaging into vesicles, receptors, transporters/degradative enzymes. Describe 2 drugs that can act on this system.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. a) Which has a higher potency? b) Which is has a higher efficacy? c) What is the approximate Kd of capsaicin in uM? (you can round to the nearest power of 10)arrow_forwardWhat is the rate-limiting-step for serotonin synthesis?arrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education





