HUMAN A&P E-TEXT ACCESS CODE
HUMAN A&P E-TEXT ACCESS CODE
11th Edition
ISBN: 9780136849063
Author: Marieb
Publisher: PEARSON
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Chapter 12, Problem 1CCS

39-Year-Old Female with Traumatic Brain Injury

Margaret Bryans, a 39-year-old female, lost control while skiing and hit her head on a tree. She regained consciousness en route to the hospital and appeared agitated and combative. Paramedics observed that she had a right hemiparesis (muscle weakness), with a nearly complete paresis of her right upper extremity and a partial paresis of the right lower extremity. A head CT scan revealed an acute subdural hematoma and an extensive subarachnoid hemorrhage. Doctors noted that she was able to follow commands from medical personnel. However, she could only speak haltingly, using simple words.

Chapter 12, Problem 1CCS, 39-Year-Old Female with Traumatic Brain Injury Margaret Bryans, a 39-year-old female, lost control

Surgery to remove large clots from the subarachnoid space was performed immediately. Two weeks after the surgery, she showed significant improvement in her speech and motor function.

1. The adult brain consists of four main anatomical regions (see Table 12.1. pp. 458–459). Based on the observed signs in this case, which of these four brain regions is involved? What evidence did you use to determine this?

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

Chapter 12 Solutions

HUMAN A&P E-TEXT ACCESS CODE

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