Laboratory Manual for Human Anatomy & Physiology Main Version
Laboratory Manual for Human Anatomy & Physiology Main Version
4th Edition
ISBN: 9781260159110
Author: Terry Martin
Publisher: Mcgraw-hill Higher Education (us)
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Chapter 12, Problem 1.3A

The bone of the thigh is an example of a(an) ____________ bone.

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You inject morpholino oligonucleotides that inhibit the translation of follistatin, chordin, and noggin (FCN) at the 1 cell stage of a frog embryo. What is the effect on neurulation in the resulting embryo? Propose an experiment that would rescue an embryo injected with FCN morpholinos.
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Plekhg5 functions in bottle cell formation, and Shroom3 functions in neural plate closure, yet the phenotype of injecting mRNA of each into the animal pole of a fertilized egg is very similar. What is the phenotype, and why is the phenotype so similar? Is the phenotype going to be that there is a disruption of the formation of the neural tube for both of these because bottle cell formation is necessary for the neural plate to fold in forming the neural tube and Shroom3 is further needed to close the neural plate? So since both Plekhg5 and Shroom3 are used in forming the neural tube, injecting the mRNA will just lead to neural tube deformity?

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Laboratory Manual for Human Anatomy & Physiology Main Version

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