Lehninger Principles of Biochemistry (Instructor's)
Lehninger Principles of Biochemistry (Instructor's)
7th Edition
ISBN: 9781319117689
Author: nelson
Publisher: MAC HIGHER
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Chapter 12, Problem 11P
Summary Introduction

To compare: The G protein-Gs that acts in transducing signal from β-adrenergic receptors and G protein Ras

Introduction: G protein is named due to their binding activity with guanine nucleotide such as GDP and GTP. They are made of three different subunits and are called heterotrimers which is associated with inner surface of plasma membrane and G protein-coupled receptors.

Summary Introduction

To explain: The properties shared by G proteins-Gs and Ras protein.

Introduction: The G proteins are made of three different subunits and are called heterotrimers which is associated with inner surface of plasma membrane and G protein-coupled receptors. It is named so due to their binding activity with guanine nucleotide such as GDP and GTP.

Summary Introduction

To explain: The difference between Gs protein and Ras protein.

Introduction: G protein consists of three subunits such as Gα, Gβ and Gγ. Gα carries a binding site for nucleotide. Gβ and Gγ are associated with inner surface of plasma membrane and G protein-coupled receptors. They are named as G protein due to their binding with guanine nucleotide such as GDP and GTP.

Summary Introduction

To determine: The functional difference between Gs and Gi.

Introduction: G protein is named due to their binding activity with guanine nucleotide such as GDP and GTP. They are made of three different subunits and are called heterotrimers which is associated with inner surface of plasma membrane and G protein-coupled receptors.

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