MICRO. FUND. CONNECT CODE W/VIRTUAL LAB
MICRO. FUND. CONNECT CODE W/VIRTUAL LAB
3rd Edition
ISBN: 9781266313806
Author: Cowan
Publisher: INTER MCG
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Chapter 11.2, Problem 7AYP
Summary Introduction

To enlist:

Several portal of entry and exit.

Concept introduction:

Microbes that can cause disease are termed as pathogens or the infectious causative agents. Microorganisms are harmful, such as bacteria, viruses and other microorganisms which cause disease are termed as pathogens. Pathogens invade tissues of the body to infect humans, plants, and other animals. Some examples of diseases caused by pathogens are common cold, tuberculosis, cholera, and chicken pox.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.
You implant an FGF10-coated bead into the anterior flank of a chicken embryo, directly below the level of the wing bud. What is the phenotype of the resulting ectopic limb?  Briefly describe the expected expression domains of 1) Shh, 2) Tbx4, and 3) Tbx5 in the resulting ectopic limb bud.

Chapter 11 Solutions

MICRO. FUND. CONNECT CODE W/VIRTUAL LAB

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