ORGANIC CHEMISTRY-NEXTGEN+BOX (2 SEM.)
ORGANIC CHEMISTRY-NEXTGEN+BOX (2 SEM.)
3rd Edition
ISBN: 9781119497479
Author: Klein
Publisher: WILEY
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Chapter 11.2, Problem 4ATS
Interpretation Introduction

Interpretation:

The reagents that are used for the conversion of the given compound 1 changed into Artemidin have to be identified.

Concept Introduction:

Bromination of alkanes:

The bromination of alkanes takes place in the presence of light. It is the conversion of alkane into monobrominated products. In the bromination of alkanes the tertiary C-H bond will get selectively brominated over secondary and secondary C-H bond will get selectively brominated over primary as shown here:

Examples:

ORGANIC CHEMISTRY-NEXTGEN+BOX (2 SEM.), Chapter 11.2, Problem 4ATS , additional homework tip  1

Conversion of brominated alkanes into alkenes:

The brominated alkanes can be converted into alkenes using the strong base such as t-BuOK which means potassium tertiary butoxide.

ORGANIC CHEMISTRY-NEXTGEN+BOX (2 SEM.), Chapter 11.2, Problem 4ATS , additional homework tip  2

The structure of t-BuOK is:

ORGANIC CHEMISTRY-NEXTGEN+BOX (2 SEM.), Chapter 11.2, Problem 4ATS , additional homework tip  3

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