IA MODIFIED MASTERING BIOLOGY WITH E TEX
IA MODIFIED MASTERING BIOLOGY WITH E TEX
12th Edition
ISBN: 9780136781752
Author: Urry
Publisher: PEARSON
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Chapter 11.1, Problem 3CC
Summary Introduction

To determine: If a cell-free mixture of epinephrine, glycogen phosphorylase and glycogen would produce glucose-1-phosphate.

Introduction:

Cell signaling requires a good amount of enzymes, precursor and intermediate products that lead to the production of the desired substrate. This cannot be achieved in a cell-free environment because of the absence of the required intermediates.

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O Macmillan Learning Glu-His-Trp-Ser-Gly-Leu-Arg-Pro-Gly The pKa values for the peptide's side chains, terminal amino groups, and carboxyl groups are provided in the table. Amino acid Amino pKa Carboxyl pKa Side-chain pKa glutamate 9.60 2.34 histidine 9.17 1.82 4.25 6.00 tryptophan 9.39 2.38 serine 9.15 2.21 glycine 9.60 2.34 leucine 9.60 2.36 arginine 9.04 2.17 12.48 proline 10.96 1.99 Calculate the net charge of the molecule at pH 3. net charge at pH 3: Calculate the net charge of the molecule at pH 8. net charge at pH 8: Calculate the net charge of the molecule at pH 11. net charge at pH 11: Estimate the isoelectric point (pl) for this peptide. pl:

Chapter 11 Solutions

IA MODIFIED MASTERING BIOLOGY WITH E TEX

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