Biology: How Life Works
3rd Edition
ISBN: 9781319017637
Author: James Morris, Daniel Hartl, Andrew Knoll, Melissa Michael, Robert Lue, Andrew Berry, Andrew Biewener, Brian Farrell, N. Michele Holbrook
Publisher: Macmillan Higher Education
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Chapter 11.1, Problem 1SAQ
Summary Introduction
To compare:
The ways in which prokaryotic cells and eukaryotic cells divide.
Introduction:
Cell division is a method by which a single cell divides into two daughter cells. The two daughter cells, each receive the genetic material present in the single parent cell. This duplication of single cell into two occurs by a series of stages that is the life cycle of every single cell. The life cycle of every single cell begins and ends with cell division.
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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.
b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake?
Options:
A. Dose; Increase dose
B. Dose; Decrease dose
C. Dose; Do not change dose
D. Interval; Increase the interval between doses (give the drug less frequently)
E. Interval; Decrease the interval between doses (give the drug more frequently)
F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
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