Chapter 11, Problem 25CQ

Summary Introduction

To explain: The reason behind substituting Ala for either Asp 101 or Arg 114 does not significantly alter the enzyme’s tertiary structure, but it significantly reduces its catalytic activity.

Concept introduction: Lysozyme is an enzyme that protects from the bacterial infection. It is an antimicrobial enzyme that forms the part of innate immune system. This enzyme is found in tears, saliva, sweat, and other body fluids.