EBK ESSENTIALS OF PATHOPHYSIOLOGY
EBK ESSENTIALS OF PATHOPHYSIOLOGY
4th Edition
ISBN: 9781469893389
Author: PORTH
Publisher: WOLTERS KLUWER HEALTH (COURSE)
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Chapter 11, Problem 1RE

A.

Summary Introduction

To Determine: The reason for the stem cell that are used rather than the mature lymphocytes as per the above information.

Introduction: B cells are the type of white blood cell whose primary role is to secreting antibodies in the humoral immunity of the adaptive immune system.

A.

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Explanation of Solution

Infectious mononucleosis is the primary immunodeficiency disorder caused by the Epstein-Barr virus (EBV). This disorder can be found in adolescents and young adults. EPV is the virus having the richest in evading the immune systems and infect an individual for a lifetime. The virus can be transmitted from person to person. Therefore the virus spreads to the underlying oropharyngeal lymphoid tissue and B-lymphocytes.

They all have the receptor for the EB virus. Infection of the B-lymphocytes can kill the infected B cells or harbor the EBV genome increase in the circulation, where it produces heterophil antibodies to diagnosis of infectious mononucleosis.

B.

Summary Introduction

To Determine: The way of stem cell that would go about the process of repopulation of the bone marrow.

Introduction: Bone marrow is the site for the production of B cells. Bone marrow is the type of spongy tissue that secretes new blood cells, platelets, and white blood cells.

B.

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Explanation of Solution

The normal immune response is essential to control the proliferation of EBV infected B cells with CD8+ cytotoxic T cells. The disorder arises abruptly with high fever, and an individual needs medical attention for major pharyngitis.

In this condition, the lymph node enlarges mainly in the cervical, axillary, and groin areas. The peripheral blood usually represents an incline number of leukocytes with white blood cells (inside the bone marrow) between 12000 to 18000 cells/µL. The rise in WBC begins from the first week and returns to the normal count in the fourth week.

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EBK ESSENTIALS OF PATHOPHYSIOLOGY

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