LAB MANUAL TO ACCOMPANY FD A+P CONNECT
4th Edition
ISBN: 9781307898811
Author: McKinley
Publisher: MCG
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Textbook Question
Chapter 11, Problem 13DYKB
Distinguish between suprahyoid and infrahyoid muscles, and describe the functions of each group.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
300
0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points
possible). You do NOT need to submit graphs or data tables.
Give the terminal regression line equation and R or R² value:
Give the x axis (name and units, if any) of the terminal line:
Give the y axis (name and units, if any) of the terminal line:
Give the residual regression line equation and R or R² value:
Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 11 Solutions
LAB MANUAL TO ACCOMPANY FD A+P CONNECT
Ch. 11.1 - Prob. 1WDYLCh. 11.1 - Which muscle is strongera pennate muscle or a...Ch. 11.1 - What is the difference between an agonist and a...Ch. 11.2 - What are some words used in muscle names that...Ch. 11.2 - The gluteus maximus muscle gets its name from...Ch. 11.3 - Prob. 7WDYLCh. 11.3 - Which extrinsic eye muscles abduct the eye (move...Ch. 11.3 - Prob. 9WDYLCh. 11.3 - Prob. 10WDYLCh. 11.3 - Prob. 11WDYL
Ch. 11.3 - Which neck muscles extend the neck? Which neck...Ch. 11.4 - Prob. 13WDYLCh. 11.5 - Prob. 14WDYLCh. 11.5 - How is the diaphragm involved in respiration?Ch. 11.6 - What are the main actions of the abdominal...Ch. 11.7 - Prob. 17WDYLCh. 11.8 - Prob. 18WDYLCh. 11.8 - Prob. 19WDYLCh. 11.8 - Identify the rotator cuff muscles, and describe...Ch. 11.8 - What are the muscles in the anterior compartment...Ch. 11.8 - Prob. 22WDYLCh. 11.8 - Prob. 23WDYLCh. 11.8 - What muscles in the posterior compartment move the...Ch. 11.8 - Prob. 25WDYLCh. 11.9 - Prob. 26WDYLCh. 11.9 - Prob. 27WDYLCh. 11.9 - Prob. 28WDYLCh. 11.9 - Prob. 29WDYLCh. 11 - _____ 1. Which statement is true about an agonist?...Ch. 11 - Which muscles bilateral action is flexion of the...Ch. 11 - _____ 3. When this large muscle contracts, the...Ch. 11 - Prob. 4DYKBCh. 11 - _____ 5. Each of these muscles can flex the...Ch. 11 - _____ 6. The dorsal interossei muscles in the hand...Ch. 11 - Prob. 7DYKBCh. 11 - Prob. 8DYKBCh. 11 - Prob. 9DYKBCh. 11 - Prob. 10DYKBCh. 11 - Prob. 11DYKBCh. 11 - Which muscles of facial expression do you use to...Ch. 11 - Distinguish between suprahyoid and infrahyoid...Ch. 11 - What is the effect of contracting the abdominal...Ch. 11 - What movements are possible at the glenohumeral...Ch. 11 - Identify the compartments of the arm (brachium),...Ch. 11 - Prob. 17DYKBCh. 11 - Prob. 18DYKBCh. 11 - What leg muscles allow a ballet dancer to rise up...Ch. 11 - Which muscles are responsible for foot inversion?Ch. 11 - Prob. 1CALCh. 11 - Prob. 2CALCh. 11 - Prob. 3CALCh. 11 - Prob. 4CALCh. 11 - Prob. 5CALCh. 11 - Prob. 1CSLCh. 11 - While training on the balance beam, Pat slipped...Ch. 11 - Why is it more difficult for Eric to lift a heavy...
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