Chapter 11, Problem 11PIAT

Summary Introduction

To review:

The events which occur after binding of the G protein when receptors bind to a pheromone.

Introduction:

When the receptor binds to the pheromone, the G protein (guanine nucleotide binding protein) gets activated. This is brought about by the phosphorylation of guanine diphosphate (GDP) to guanine triphosphate (GTP). Yeast cells secrete signaling molecules called pheromones that are specific for their mating type. Type α cells produce the pheromone α factor, which binds to a G-protein-coupled receptor on type a cells, and vice versa.