Concept explainers
A two-stage clinical trial is planned for testing H0: p = .10 versus Ha: p > .10, where p is the proportion of responders among patients who were treated by the protocol treatment. At the first stage, 15 patients are accrued and treated. If 4 or more responders are observed among the (first) 15 patients, H0 is rejected, the study is terminated, and no more patients are accrued. Otherwise, another 15 patients will be accrued and treated in the second stage. If a total of 6 or more responders are observed among the 30 patients accrued in the two stages (15 in the first stage and 15 more in the second stage), then H0 is rejected. For example, if 5 responders are found among the first-stage patients, H0 is rejected and the study is over. However, if 2 responders are found among the first-stage patients, 15 second-stage patients are accrued, and an additional 4 or more responders (for a total of 6 or more among the 30) are identified, H0 is rejected and the study is over.1
a Use the binomial table to find the numerical value of α for this testing procedure.
b Use the binomial table to find the
c For the rejection region defined above, find β if p = .30.
Trending nowThis is a popular solution!
Chapter 10 Solutions
Mathematical Statistics with Applications
- Let X be a random variable with support SX = {−3, 0.5, 3, −2.5, 3.5}. Part ofits probability mass function (PMF) is given bypX(−3) = 0.15, pX(−2.5) = 0.3, pX(3) = 0.2, pX(3.5) = 0.15.(a) Find pX(0.5).(b) Find the cumulative distribution function (CDF), FX(x), of X.1(c) Sketch the graph of FX(x).arrow_forwardA well-known company predominantly makes flat pack furniture for students. Variability with the automated machinery means the wood components are cut with a standard deviation in length of 0.45 mm. After they are cut the components are measured. If their length is more than 1.2 mm from the required length, the components are rejected. a) Calculate the percentage of components that get rejected. b) In a manufacturing run of 1000 units, how many are expected to be rejected? c) The company wishes to install more accurate equipment in order to reduce the rejection rate by one-half, using the same ±1.2mm rejection criterion. Calculate the maximum acceptable standard deviation of the new process.arrow_forward5. Let X and Y be independent random variables and let the superscripts denote symmetrization (recall Sect. 3.6). Show that (X + Y) X+ys.arrow_forward
- 8. Suppose that the moments of the random variable X are constant, that is, suppose that EX" =c for all n ≥ 1, for some constant c. Find the distribution of X.arrow_forward9. The concentration function of a random variable X is defined as Qx(h) = sup P(x ≤ X ≤x+h), h>0. Show that, if X and Y are independent random variables, then Qx+y (h) min{Qx(h). Qr (h)).arrow_forward10. Prove that, if (t)=1+0(12) as asf->> O is a characteristic function, then p = 1.arrow_forward
- 9. The concentration function of a random variable X is defined as Qx(h) sup P(x ≤x≤x+h), h>0. (b) Is it true that Qx(ah) =aQx (h)?arrow_forward3. Let X1, X2,..., X, be independent, Exp(1)-distributed random variables, and set V₁₁ = max Xk and W₁ = X₁+x+x+ Isk≤narrow_forward7. Consider the function (t)=(1+|t|)e, ER. (a) Prove that is a characteristic function. (b) Prove that the corresponding distribution is absolutely continuous. (c) Prove, departing from itself, that the distribution has finite mean and variance. (d) Prove, without computation, that the mean equals 0. (e) Compute the density.arrow_forward
- 1. Show, by using characteristic, or moment generating functions, that if fx(x) = ½ex, -∞0 < x < ∞, then XY₁ - Y2, where Y₁ and Y2 are independent, exponentially distributed random variables.arrow_forward1. Show, by using characteristic, or moment generating functions, that if 1 fx(x): x) = ½exarrow_forward1990) 02-02 50% mesob berceus +7 What's the probability of getting more than 1 head on 10 flips of a fair coin?arrow_forward
- Glencoe Algebra 1, Student Edition, 9780079039897...AlgebraISBN:9780079039897Author:CarterPublisher:McGraw HillBig Ideas Math A Bridge To Success Algebra 1: Stu...AlgebraISBN:9781680331141Author:HOUGHTON MIFFLIN HARCOURTPublisher:Houghton Mifflin Harcourt
- Holt Mcdougal Larson Pre-algebra: Student Edition...AlgebraISBN:9780547587776Author:HOLT MCDOUGALPublisher:HOLT MCDOUGALCollege Algebra (MindTap Course List)AlgebraISBN:9781305652231Author:R. David Gustafson, Jeff HughesPublisher:Cengage Learning