One reaction that occurs in human metabolism is For this reaction Δ G ° =14 kJ at 25°C. a. Calculate K for this reaction at 25°C. b. In a living cell this reaction is coupled with thehydrolysis of ATP. (See Exercise 84.) Calculate Δ G ° and K at 25°C for the following reaction: Glutamic acid( a q )+ATP( a q )+NH 3 ( a q ) ⇌ Glutamine( a q )+ADP( a q )+H 2 PO 4 – ( a q )
One reaction that occurs in human metabolism is For this reaction Δ G ° =14 kJ at 25°C. a. Calculate K for this reaction at 25°C. b. In a living cell this reaction is coupled with thehydrolysis of ATP. (See Exercise 84.) Calculate Δ G ° and K at 25°C for the following reaction: Glutamic acid( a q )+ATP( a q )+NH 3 ( a q ) ⇌ Glutamine( a q )+ADP( a q )+H 2 PO 4 – ( a q )
Solution Summary: The author explains that the Gibbs free energy for a reaction at equilibrium is related to the equilibrium constant (K) through the 'Begin'-arrayl'.
One reaction that occurs in human metabolism is For this reaction
Δ
G
° =14 kJ
at 25°C. a. Calculate K for this reaction at 25°C. b. In a living cell this reaction is coupled with thehydrolysis of ATP. (See Exercise 84.) Calculate
Δ
G
°
and K at 25°C for the following reaction:
Glutamic acid(
a
q
)+ATP(
a
q
)+NH
3
(
a
q
)
⇌
Glutamine(
a
q
)+ADP(
a
q
)+H
2
PO
4
–
(
a
q
)
Chemical pathways by which living things function, especially those that provide cellular energy, such as the transformation of energy from food into the energy of ATP. Metabolism also focuses on chemical pathways involving the synthesis of new biomolecules and the elimination of waste.
1. Calculate the accurate monoisotopic mass (using all 1H, 12C, 14N, 160 and 35CI) for your product using the table in
your lab manual. Don't include the Cl, since you should only have [M+H]*. Compare this to the value you see on
the LC-MS printout. How much different are they?
2. There are four isotopic peaks for the [M+H]* ion at m/z 240, 241, 242 and 243. For one point of extra credit,
explain what each of these is and why they are present.
3. There is a fragment ion at m/z 184. For one point of extra credit, identify this fragment and confirm by
calculating the accurate monoisotopic mass.
4. The UV spectrum is also at the bottom of your printout. For one point of extra credit, look up the UV spectrum
of bupropion on Google Images and compare to your spectrum. Do they match? Cite your source.
5. For most of you, there will be a second chromatographic peak whose m/z is 74 (to a round number). For one
point of extra credit, see if you can identify this molecule as well and confirm by…
Please draw, not just describe!
can you draw each step on a piece of a paper please this is very confusing to me
Chapter 10 Solutions
WebAssign for Zumdahl's Chemical Principles, 8th Edition [Instant Access], Single-Term
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