BIOCHEMISTRY W/1 TERM ACHEIVE ACCESS
BIOCHEMISTRY W/1 TERM ACHEIVE ACCESS
9th Edition
ISBN: 9781319425746
Author: BERG
Publisher: MAC HIGHER
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Chapter 10, Problem 6P
Interpretation Introduction

Interpretation:

The meaning of the biochemical rationale for ATP serving as a positive regulator of ATCase is to be stated.

Concept introduction:

Enzymes being the catalysts increase the rate of reaction. In an enzyme-catalyzed reaction, the rate of reaction for the product formation depends on the concentration of enzyme as well as the substrate involved in the reaction via formation of an enzyme substrate complex.The enzyme which is able to do the conformational changes if an effector gets attached to it is known as allosteric enzyme.

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Please draw out the mechanism with curved arrows showing electron flow. Pyruvate is accepted into the TCA cycle by a “feeder” reaction using the pyruvate dehydrogenase complex, resulting in acetyl-CoA and CO2. Provide the mechanism for this reaction utilizing the TPP cofactor. Include the roles of all cofactors.
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