EP INTRODUCTORY STATISTICS-MYSTATLAB
3rd Edition
ISBN: 9780135190210
Author: Gould
Publisher: PEARSON CO
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Chapter 10, Problem 46SE
Multiple Sclerosis Treatment In a 2018 article published in The Lancet, Kappos et al. studied the effect of the drug siponimod in treating patients with secondary progressive multiple sclerosis (SPMS) using a double-blind, randomized, controlled study. Of the 1099 patients given the drug, 198 experienced a severe adverse outcome. Of the 546 patients given the placebo, 82 experienced a severe adverse outcome.
a. Find the percentage in each group that suffered a severe adverse outcome.
b. Create a two-way table with the treatment labels (drug/placebo) across the top.
c. Test the hypothesis that treatment and severe adverse outcome are associated using a significance level of
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- We calculated that a target sample size of 3626, which was based on anticipated baseline 90-day mortality of 22% and a noninferiority margin of no more than 4 percentage points, would give the trial 80% power, at a one-sided alpha level of 2.5%, accounting for a maximum of 5% loss to follow-up and for early stopping rules for three interim analyses.-
Can you help me understand this analysis?
A 95.7% confidence interval is shown for the intention-to-treat analysis (accounting for alpha spending in interim analyses), and 95% confidence intervals are shown for the other two analyses. The widths of the confidence intervals have not been adjusted for multiplicity. The dashed line indicates the noninferiority margin of 4 percentage points.
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Chapter 10 Solutions
EP INTRODUCTORY STATISTICS-MYSTATLAB
Ch. 10 - Tests a. In Chapter 8, you learned some tests of...Ch. 10 - In Chapter 9, you learned some tests of means. Are...Ch. 10 - Crime and Gender A statistics student conducted a...Ch. 10 - Red Cars and Stop Signs The table shows the raw...Ch. 10 - The table summarizes the outcomes of a study that...Ch. 10 - Finger Length There is a theory that relative...Ch. 10 - Student Loans-California According to a 2017...Ch. 10 - Student Loans-Illinois According to a 2017 report,...Ch. 10 - Breakfast Habits (Example 1 2) In a 2015 study by...Ch. 10 - Fast Food Habits In the study referenced in...
Ch. 10 - Mummies with Heart Disease According to the...Ch. 10 - Texting While Driving According to the 2015 High...Ch. 10 - Violins Stradivarius violins, made in the 1700s by...Ch. 10 - Coin Flips You flip a coin 100 times and get 58...Ch. 10 - Prob. 15SECh. 10 - Prob. 16SECh. 10 - Are Humans Like Random Number Generators? (Example...Ch. 10 - Is the Random Number Table Really Random? We...Ch. 10 - Coin Spins A penny was spun on a hard, flat...Ch. 10 - Internet Usage In 2018 Pew Research reported that...Ch. 10 - Dreidel Spinning When playing Dreidel, (see photo)...Ch. 10 - Plastic Dreidel See exercise 10.21 for an...Ch. 10 - Is the Six-Sided Die Fair? The table shows the...Ch. 10 - Is the Six-Sided Die Fair? Repeat the chi-square...Ch. 10 - Violins Professional musicians listened to five...Ch. 10 - Mummies with Heart Disease Exercise 10.11 on...Ch. 10 - Party and Right Direction (Example 4) Suppose a...Ch. 10 - Antibiotic or Placebo A large number of surgery...Ch. 10 - Relevant Education (Example 5) A 2018 Gallup poll...Ch. 10 - Prob. 30SECh. 10 - Fitness The table shows the percentage of all men...Ch. 10 - Food Security The table shows the percentage of...Ch. 10 - Fitness App Use and Gender (Example 6) In a 2015...Ch. 10 - Diet App Use and Gender In the study referenced in...Ch. 10 - HPV Vaccination Rates A vaccine is available to...Ch. 10 - HPV Vaccine Literacy Rates In the study described...Ch. 10 - Gender and Happiness of Marriage The table shows...Ch. 10 - Is Smiling Independent of Age? Randomly chosen...Ch. 10 - Preschool Attendance and High School Graduation...Ch. 10 - Preschool Attendance and High School Graduation...Ch. 10 - Preschool Attendance and High School Graduation...Ch. 10 - Prob. 42SECh. 10 - Prob. 43SECh. 10 - Marijuana Legalization The 2018 Pew Research poll...Ch. 10 - Brain Bleed Treatment In a 2018 article published...Ch. 10 - Multiple Sclerosis Treatment In a 2018 article...Ch. 10 - Prob. 47SECh. 10 - Political Party Affiliation and Generation A 2018...Ch. 10 - Prob. 49SECh. 10 - Night Shifts A random sample of nurses working...Ch. 10 - Gender and Political Party Affiliation The data in...Ch. 10 - Children and Happiness The data in the table come...Ch. 10 - Prob. 53SECh. 10 - Nice Rats Rats had a choice of freeing another rat...Ch. 10 - Peanut Allergies In a 2015 study reported in the...Ch. 10 - Peanut Allergies In the study described in...Ch. 10 - Prob. 57CRECh. 10 - In exercises 10.57 to 10.64, choose an appropriate...Ch. 10 - Prob. 59CRECh. 10 - Prob. 60CRECh. 10 - Prob. 61CRECh. 10 - In exercises 10.57 to 10.64, choose an appropriate...Ch. 10 - Prob. 63CRECh. 10 - In exercises 10.57 to 10.64, choose an appropriate...Ch. 10 - Perry Preschool Arrests The Perry Preschool...Ch. 10 - Parental Training and Criminal Behavior of...Ch. 10 - Prob. 67CRECh. 10 - Prob. 68CRECh. 10 - Harassment in the Workplace An 2017 NPR/Marist...Ch. 10 - Prob. 70CRECh. 10 - Robot Cockroaches Cockroaches tend to rest in...Ch. 10 - Robot Cockroaches Refer to the description in...Ch. 10 - Prob. 73CRECh. 10 - Conviction Rate with Opposite Race Here are the...
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