BIOL 105 LIVING WORLD CONNECT CARD
BIOL 105 LIVING WORLD CONNECT CARD
9th Edition
ISBN: 9781260419979
Author: Johnson
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 10, Problem 3IA

a.

Summary Introduction

To explain: Whether woolly hair is a sex-linked or autosomal.

Introduction: Woolly-haired is a rare congenital disease that is indicated by extreme kinkiness of the hair. The fragile hair may be present at birth or appear in the first month. It may be due to homozygous or heterozygous mutations in the gene lipase H and lysophosphatidic acid receptor 6. These two genes work together for hair growth and texture. It may be autosomal dominant hereditary woolly hair or autosomal recessive familial woolly hair.

b.

Summary Introduction

To determine: Whether the woolly-hair trait is dominant or recessive.

c.

Summary Introduction

To determine: Whether the woolly-hair trait given is determined by a single gene or multiple genes.

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A sample of blood was taken from the above individual and prepared for haemoglobin analysis. However, when water was added the cells did not lyse and looked normal in size and shape. The technician suspected that they had may have made an error in the protocol – what is the most likely explanation?   The cell membranes are more resistant than normal.   An isotonic solution had been added instead of water.   A solution of 0.1 M NaCl had been added instead of water.   Not enough water had been added to the red blood cell pellet.   The man had sickle-cell anaemia.
A sample of blood was taken from the above individual and prepared for haemoglobin analysis. However, when water was added the cells did not lyse and looked normal in size and shape. The technician suspected that they had may have made an error in the protocol – what is the most likely explanation?   The cell membranes are more resistant than normal.   An isotonic solution had been added instead of water.   A solution of 0.1 M NaCl had been added instead of water.   Not enough water had been added to the red blood cell pellet.   The man had sickle-cell anaemia.
With reference to their absorption spectra of the oxy haemoglobin intact line) and deoxyhemoglobin (broken line) shown in Figure 2 below, how would you best explain the reason why there are differences in the major peaks of the spectra? Figure 2. SPECTRA OF OXYGENATED AND DEOXYGENATED HAEMOGLOBIN OBTAINED WITH THE RECORDING SPECTROPHOTOMETER 1.4 Abs < 0.8 06 0.4 400 420 440 460 480 500 520 540 560 580 600 nm 1. The difference in the spectra is due to a pH change in the deoxy-haemoglobin due to uptake of CO2- 2. There is more oxygen-carrying plasma in the oxy-haemoglobin sample. 3. The change in Mr due to oxygen binding causes the oxy haemoglobin to have a higher absorbance peak. 4. Oxy-haemoglobin is contaminated by carbaminohemoglobin, and therefore has a higher absorbance peak 5. Oxy-haemoglobin absorbs more light of blue wavelengths and less of red wavelengths than deoxy-haemoglobin
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