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Anatomy & Physiology
3rd Edition
ISBN: 9781259398629
Author: McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher: Mcgraw Hill Education,
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Concept explainers
Question
Chapter 10, Problem 1CSL
Summary Introduction
To explain:
The reason that body becomes stiff after death.
Concept introduction:
Rigor mortis is the third stage of the death that is caused by chemical changes in the muscle resulting in stiffening of the body. In humans, rigor mortis occurs after 4 hours of death.
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Please answer the following chart so I can understand how to do it.
Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
300
0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points
possible). You do NOT need to submit graphs or data tables.
Give the terminal regression line equation and R or R² value:
Give the x axis (name and units, if any) of the terminal line:
Give the y axis (name and units, if any) of the terminal line:
Give the residual regression line equation and R or R² value:
Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 10 Solutions
Anatomy & Physiology
Ch. 10.1 - Prob. 1LOCh. 10.1 - What are the five major functions of skeletal...Ch. 10.1 - Prob. 2LOCh. 10.1 - Explain the skeletal muscle characteristics of...Ch. 10.2 - Prob. 3LOCh. 10.2 - Prob. 4LOCh. 10.2 - Prob. 5LOCh. 10.2 - Prob. 1WDTCh. 10.2 - Identify the location and function of these...Ch. 10.2 - Prob. 6LO
Ch. 10.2 - Prob. 7LOCh. 10.2 - LEARNING OBJECTIVES
8. Distinguish between thick...Ch. 10.2 - Prob. 9LOCh. 10.2 - Prob. 10LOCh. 10.2 - Prob. 2WDTCh. 10.2 - Draw and label a diagram of a sarcomere.Ch. 10.2 - Prob. 5WDLCh. 10.2 - Prob. 11LOCh. 10.2 - Prob. 12LOCh. 10.2 - Prob. 6WDLCh. 10.2 - Diagram and label the anatomic structures of a...Ch. 10.2 - Prob. 13LOCh. 10.2 - Prob. 8WDLCh. 10.3 - Prob. 14LOCh. 10.3 - What triggers the binding of synaptic vesicles to...Ch. 10.3 - Prob. 15LOCh. 10.3 - What two events are linked in the physiologic...Ch. 10.3 - Prob. 11WDLCh. 10.3 - Prob. 16LOCh. 10.3 - Prob. 3WDTCh. 10.3 - Prob. 12WDLCh. 10.3 - Describe the four processes that repeat in...Ch. 10.3 - What causes the release of the myosin head from...Ch. 10.3 - LEARNING OBJECTIVES
17. Discuss what happens to...Ch. 10.3 - Prob. 18LOCh. 10.3 - How do acetylcholinesterase and Ca2+ pumps...Ch. 10.4 - LEARNING OBJECTIVES
19. Describe how ATP is made...Ch. 10.4 - Prob. 20LOCh. 10.4 - Prob. 4WDTCh. 10.4 - Prob. 16WDLCh. 10.4 - What are the various means for making ATP...Ch. 10.4 - Prob. 21LOCh. 10.4 - Prob. 18WDLCh. 10.5 - Prob. 22LOCh. 10.5 - Prob. 19WDLCh. 10.5 - Prob. 23LOCh. 10.5 - Prob. 20WDLCh. 10.5 - Prob. 24LOCh. 10.5 - Prob. 21WDLCh. 10.6 - LEARNING OBJECTIVE
25. Describe what occurs in a...Ch. 10.6 - Prob. 5WDTCh. 10.6 - What events are occurring in a muscle that produce...Ch. 10.6 - Prob. 26LOCh. 10.6 - What is recruitment? Explain its importance in the...Ch. 10.6 - Prob. 27LOCh. 10.6 - Prob. 24WDLCh. 10.7 - Prob. 28LOCh. 10.7 - What is the function of skeletal muscle tone?Ch. 10.7 - LEARNING OBJECTIVE
29. Distinguish between...Ch. 10.7 - When you flex your biceps brachii while doing...Ch. 10.7 - LEARNING OBJECTIVE
30. Explain the length-tension...Ch. 10.7 - Prob. 27WDLCh. 10.7 - Prob. 31LOCh. 10.7 - How can muscle fatigue result from changes in each...Ch. 10.8 - LEARNING OBJECTIVE
32. Compare and contrast the...Ch. 10.8 - Prob. 29WDLCh. 10.8 - Prob. 33LOCh. 10.8 - Prob. 30WDLCh. 10.9 - Prob. 34LOCh. 10.9 - What are three anatomic or physiologic differences...Ch. 10.10 - Prob. 35LOCh. 10.10 - Prob. 32WDLCh. 10.10 - LEARNING OBJECTIVE
36. Compare the microscopic...Ch. 10.10 - Prob. 33WDLCh. 10.10 - Prob. 34WDLCh. 10.10 - Prob. 37LOCh. 10.10 - What are the steps of smooth muscle contraction?Ch. 10.10 - What unique characteristics of smooth muscle allow...Ch. 10.10 - Prob. 38LOCh. 10.10 - Prob. 37WDLCh. 10.10 - Prob. 38WDLCh. 10.10 - Prob. 39LOCh. 10.10 - LEARNING OBJECTIVES
40. Compare the location and...Ch. 10.10 - Prob. 39WDLCh. 10 - Prob. 1DYBCh. 10 - The physiologic event that takes place at the...Ch. 10 - In a skeletal muscle fiber, Ca2+ is released from...Ch. 10 - The bundle of dense regular connective tissue that...Ch. 10 - In excitation-contraction coupling, the transverse...Ch. 10 - During muscle contraction, the I band a. hides the...Ch. 10 - During a concentric contraction of a muscle fiber,...Ch. 10 - What event causes a troponin-tropomyosin complex...Ch. 10 - In sustained, moderate exercise, skeletal muscle...Ch. 10 - Skeletal muscle and cardiac muscle are similar in...Ch. 10 - Explain the structural relationship between a...Ch. 10 - Prob. 12DYBCh. 10 - Prob. 13DYBCh. 10 - Put the following skeletal muscle contraction...Ch. 10 - Explain the various means of providing ATP for...Ch. 10 - Explain why athletes who excel at short sprints...Ch. 10 - Explain why skeletal muscle generates the most...Ch. 10 - Prob. 18DYBCh. 10 - Describe the response of smooth muscle to...Ch. 10 - Prob. 20DYBCh. 10 - Prob. 1CALCh. 10 - One of the primary reasons that one individual is...Ch. 10 - Prob. 3CALCh. 10 - Rigor mortis occurs following death because a....Ch. 10 - Prob. 5CALCh. 10 - Prob. 1CSLCh. 10 - Describe the effect of the botulinum toxin, which...Ch. 10 - Smooth muscle is within the urinary bladder wall....
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