CAMPBELL'S BIOLOGY MASTERING BIOLOGY
12th Edition
ISBN: 9780135855843
Author: Urry
Publisher: PEARSON
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Chapter 10, Problem 12TYU
SYNTHESIZE YOUR KNOWLEDGE
“Watennelon snow” in Antarctica is caused by a species of photosynthetic green algae that thrives in subzero temperatures (Chlamydomonas nivalis). These algae areaalsofound in high- altitude year-round snowfields. In both locations, UV light levels tend to be high. Based on what you learned in this chapter, proposc an explanation for why thisphotosyntheticalga appears reddish-pink.
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1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine:
(a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data (c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip
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2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0
Note that a µCi is a measure of the amount of radioactivity and hence is a measure of the amount of drug present. Given that the oral bioavailability of this drug is known to be essentially 100%, estimate the following from this…
The current nutrition labelling regulation in Hong Kong requires food manufacturer to list E+7 information on the package of pre-packaged food products. Do you think that more nutrients, such as calcium and cholesterol, shall be included?
Chapter 10 Solutions
CAMPBELL'S BIOLOGY MASTERING BIOLOGY
Ch. 10.1 - Prob. 1CCCh. 10.1 - Prob. 2CCCh. 10.2 - Prob. 1CCCh. 10.2 - Prob. 2CCCh. 10.2 - Prob. 3CCCh. 10.3 - Prob. 1CCCh. 10.3 - Prob. 2CCCh. 10.3 - Prob. 3CCCh. 10.4 - Prob. 1CCCh. 10.4 - Prob. 2CC
Ch. 10.4 - Prob. 3CCCh. 10.4 - Prob. 4CCCh. 10.4 - Prob. 5CCCh. 10.5 - Prob. 1CCCh. 10.5 - Prob. 2CCCh. 10.5 - Prob. 3CCCh. 10.5 - Prob. 4CCCh. 10.6 - Prob. 1CCCh. 10 - Prob. 10.1CRCh. 10 - Prob. 10.2CRCh. 10 - Prob. 10.3CRCh. 10 - Prob. 10.4CRCh. 10 - Prob. 10.5CRCh. 10 - Prob. 10.6CRCh. 10 - The light reactions of photosynthesis supply the...Ch. 10 - Which of the following sequences correctly...Ch. 10 - How is photosynthesis similar in C4 plants and CAM...Ch. 10 - Prob. 4TYUCh. 10 - Prob. 5TYUCh. 10 - In mechanism, photophosphorylation is most similar...Ch. 10 - Prob. 7TYUCh. 10 - Prob. 8TYUCh. 10 - EVOLUTION CONNECTION Photorespiration can decrease...Ch. 10 - SCIENTIFIC INQUIRY MAKE CONNECTIONS The following...Ch. 10 - Prob. 11TYUCh. 10 - SYNTHESIZE YOUR KNOWLEDGE Watennelon snow in...
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