The effects on growth of a homozygous knockout of enzyme 3 in the amino acid biosynthetic pathway [A-B-C-D- amino acid] which were catalysed by Enzymes 1,2,3 and 4 respectively. Introduction: The gene knockout is now a day becomes very important key point to study the gene impacts and its importance in the genetics.

Question

Want to see more full solutions like this?

Answer 1

Question

Chapter 10, Problem 1.1Q

Summary Introduction

To determine: The effects on growth of a homozygous knockout of enzyme 3 in the amino acid biosynthetic pathway [A-B-C-D- amino acid] which were catalysed by Enzymes 1,2,3 and 4 respectively.

Introduction: The gene knockout is now a day becomes very important key point to study the gene impacts and its importance in the genetics.

Expert Solution

Explanation of Solution

The below amino acid pathway is, in which at every step an enzyme is consumed to produce the next one:

A1⇒B2⇒C3⇒D4⇒Amino Acid

Since the above-mentioned pathway shows homozygous knocked out of enzyme 3, which supports One Gene One Enzyme hypotheses, in that case, the pathway stops after C, as there is no enzyme present which converts the C to D in the above pathway.

Summary Introduction

To determine: The means by which the points by these impacts be redressed.

Introduction: In heterozygous knockout one gene from the allele is knocked out while in homozygous both the genes from the same allele are knocked out.

Expert Solution

Explanation of Solution

The below pathway is supported by one gene-one enzyme hypothesis. The enzyme 3 is absent after homozygous knocking out due to which the fourth step is not completed yet.

A1⇒B2⇒C3⇒D4⇒Amino Acid

Hence, knockouts of metabolic pathways are acquired as single genes, suggesting that one gene encodes one polypeptide. An organism can survive the homozygous knockout of the gene for an enzyme in a critical metabolic pathway if it is supplied with the metabolites required in later stages of the pathway.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Students have asked these similar questions

If you transplant trunk neural crest into the cranial neural crest region of a developing embryo, will you see the donor tissue form cartilage? Does the neural crest only give rise to two cells in the developing embryo, and is essential for lamprey to develop their jaw structure? Does a multipotent neural crest cell that is receiving Wnt signals become a Chromaffin cell?

Using quail and chick embryos, quail-specific antibody and fluorescent tissue-specific antibodies, design an experiment where you investigate the tissues the cranial neural crest can give rise to. What are four derivatives of the cranial neural crest that you expect to see in the resulting chimeric embryos?

Does the neural crest have to undergo epithelial to mesenchymal transition prior to migration through the developing embryo? Does the neural crest differentiate into different cell types based on their axial position along the anterior and posterior axis?

Answer 2

Question

Chapter 10, Problem 1.1Q

Summary Introduction

To determine: The effects on growth of a homozygous knockout of enzyme 3 in the amino acid biosynthetic pathway [A-B-C-D- amino acid] which were catalysed by Enzymes 1,2,3 and 4 respectively.

Introduction: The gene knockout is now a day becomes very important key point to study the gene impacts and its importance in the genetics.

Expert Solution

Explanation of Solution

The below amino acid pathway is, in which at every step an enzyme is consumed to produce the next one:

A1⇒B2⇒C3⇒D4⇒Amino Acid

Since the above-mentioned pathway shows homozygous knocked out of enzyme 3, which supports One Gene One Enzyme hypotheses, in that case, the pathway stops after C, as there is no enzyme present which converts the C to D in the above pathway.

Summary Introduction

To determine: The means by which the points by these impacts be redressed.

Introduction: In heterozygous knockout one gene from the allele is knocked out while in homozygous both the genes from the same allele are knocked out.

Expert Solution

Explanation of Solution

The below pathway is supported by one gene-one enzyme hypothesis. The enzyme 3 is absent after homozygous knocking out due to which the fourth step is not completed yet.

A1⇒B2⇒C3⇒D4⇒Amino Acid

Hence, knockouts of metabolic pathways are acquired as single genes, suggesting that one gene encodes one polypeptide. An organism can survive the homozygous knockout of the gene for an enzyme in a critical metabolic pathway if it is supplied with the metabolites required in later stages of the pathway.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 3

Question

Chapter 10, Problem 1.1Q

Summary Introduction

To determine: The effects on growth of a homozygous knockout of enzyme 3 in the amino acid biosynthetic pathway [A-B-C-D- amino acid] which were catalysed by Enzymes 1,2,3 and 4 respectively.

Introduction: The gene knockout is now a day becomes very important key point to study the gene impacts and its importance in the genetics.

Expert Solution

Explanation of Solution

The below amino acid pathway is, in which at every step an enzyme is consumed to produce the next one:

A1⇒B2⇒C3⇒D4⇒Amino Acid

Since the above-mentioned pathway shows homozygous knocked out of enzyme 3, which supports One Gene One Enzyme hypotheses, in that case, the pathway stops after C, as there is no enzyme present which converts the C to D in the above pathway.

Summary Introduction

To determine: The means by which the points by these impacts be redressed.

Introduction: In heterozygous knockout one gene from the allele is knocked out while in homozygous both the genes from the same allele are knocked out.

Expert Solution

Explanation of Solution

The below pathway is supported by one gene-one enzyme hypothesis. The enzyme 3 is absent after homozygous knocking out due to which the fourth step is not completed yet.

A1⇒B2⇒C3⇒D4⇒Amino Acid

Hence, knockouts of metabolic pathways are acquired as single genes, suggesting that one gene encodes one polypeptide. An organism can survive the homozygous knockout of the gene for an enzyme in a critical metabolic pathway if it is supplied with the metabolites required in later stages of the pathway.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 4

Question

Chapter 10, Problem 1.1Q

Summary Introduction

To determine: The effects on growth of a homozygous knockout of enzyme 3 in the amino acid biosynthetic pathway [A-B-C-D- amino acid] which were catalysed by Enzymes 1,2,3 and 4 respectively.

Introduction: The gene knockout is now a day becomes very important key point to study the gene impacts and its importance in the genetics.

Expert Solution

Explanation of Solution

The below amino acid pathway is, in which at every step an enzyme is consumed to produce the next one:

A1⇒B2⇒C3⇒D4⇒Amino Acid

Since the above-mentioned pathway shows homozygous knocked out of enzyme 3, which supports One Gene One Enzyme hypotheses, in that case, the pathway stops after C, as there is no enzyme present which converts the C to D in the above pathway.

Summary Introduction

To determine: The means by which the points by these impacts be redressed.

Introduction: In heterozygous knockout one gene from the allele is knocked out while in homozygous both the genes from the same allele are knocked out.

Expert Solution

Explanation of Solution

The below pathway is supported by one gene-one enzyme hypothesis. The enzyme 3 is absent after homozygous knocking out due to which the fourth step is not completed yet.

A1⇒B2⇒C3⇒D4⇒Amino Acid

Hence, knockouts of metabolic pathways are acquired as single genes, suggesting that one gene encodes one polypeptide. An organism can survive the homozygous knockout of the gene for an enzyme in a critical metabolic pathway if it is supplied with the metabolites required in later stages of the pathway.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Chapter 10, Problem 1.1Q

Summary Introduction

To determine: The effects on growth of a homozygous knockout of enzyme 3 in the amino acid biosynthetic pathway [A-B-C-D- amino acid] which were catalysed by Enzymes 1,2,3 and 4 respectively.

Introduction: The gene knockout is now a day becomes very important key point to study the gene impacts and its importance in the genetics.

Expert Solution

Explanation of Solution

The below amino acid pathway is, in which at every step an enzyme is consumed to produce the next one:

A1⇒B2⇒C3⇒D4⇒Amino Acid

Since the above-mentioned pathway shows homozygous knocked out of enzyme 3, which supports One Gene One Enzyme hypotheses, in that case, the pathway stops after C, as there is no enzyme present which converts the C to D in the above pathway.

Summary Introduction

To determine: The means by which the points by these impacts be redressed.

Introduction: In heterozygous knockout one gene from the allele is knocked out while in homozygous both the genes from the same allele are knocked out.

Expert Solution

Explanation of Solution

The below pathway is supported by one gene-one enzyme hypothesis. The enzyme 3 is absent after homozygous knocking out due to which the fourth step is not completed yet.

A1⇒B2⇒C3⇒D4⇒Amino Acid

Hence, knockouts of metabolic pathways are acquired as single genes, suggesting that one gene encodes one polypeptide. An organism can survive the homozygous knockout of the gene for an enzyme in a critical metabolic pathway if it is supplied with the metabolites required in later stages of the pathway.

Answer 6

Chapter 10, Problem 1.1Q

Summary Introduction

To determine: The effects on growth of a homozygous knockout of enzyme 3 in the amino acid biosynthetic pathway [A-B-C-D- amino acid] which were catalysed by Enzymes 1,2,3 and 4 respectively.

Introduction: The gene knockout is now a day becomes very important key point to study the gene impacts and its importance in the genetics.

Expert Solution

Explanation of Solution

The below amino acid pathway is, in which at every step an enzyme is consumed to produce the next one:

A1⇒B2⇒C3⇒D4⇒Amino Acid

Since the above-mentioned pathway shows homozygous knocked out of enzyme 3, which supports One Gene One Enzyme hypotheses, in that case, the pathway stops after C, as there is no enzyme present which converts the C to D in the above pathway.

Answer 7

Chapter 10, Problem 1.1Q

Summary Introduction

To determine: The effects on growth of a homozygous knockout of enzyme 3 in the amino acid biosynthetic pathway [A-B-C-D- amino acid] which were catalysed by Enzymes 1,2,3 and 4 respectively.

Introduction: The gene knockout is now a day becomes very important key point to study the gene impacts and its importance in the genetics.

Answer 8

Expert Solution

Explanation of Solution

The below amino acid pathway is, in which at every step an enzyme is consumed to produce the next one:

A1⇒B2⇒C3⇒D4⇒Amino Acid

Since the above-mentioned pathway shows homozygous knocked out of enzyme 3, which supports One Gene One Enzyme hypotheses, in that case, the pathway stops after C, as there is no enzyme present which converts the C to D in the above pathway.

Answer 9

Expert Solution

Answer 10

Expert Solution

Answer 11

Expert Solution

Answer 12

Summary Introduction

To determine: The means by which the points by these impacts be redressed.

Introduction: In heterozygous knockout one gene from the allele is knocked out while in homozygous both the genes from the same allele are knocked out.

Expert Solution

Explanation of Solution

The below pathway is supported by one gene-one enzyme hypothesis. The enzyme 3 is absent after homozygous knocking out due to which the fourth step is not completed yet.

A1⇒B2⇒C3⇒D4⇒Amino Acid

Hence, knockouts of metabolic pathways are acquired as single genes, suggesting that one gene encodes one polypeptide. An organism can survive the homozygous knockout of the gene for an enzyme in a critical metabolic pathway if it is supplied with the metabolites required in later stages of the pathway.

Answer 13

Summary Introduction

To determine: The means by which the points by these impacts be redressed.

Introduction: In heterozygous knockout one gene from the allele is knocked out while in homozygous both the genes from the same allele are knocked out.

Answer 14

Expert Solution

Explanation of Solution

The below pathway is supported by one gene-one enzyme hypothesis. The enzyme 3 is absent after homozygous knocking out due to which the fourth step is not completed yet.

A1⇒B2⇒C3⇒D4⇒Amino Acid

Hence, knockouts of metabolic pathways are acquired as single genes, suggesting that one gene encodes one polypeptide. An organism can survive the homozygous knockout of the gene for an enzyme in a critical metabolic pathway if it is supplied with the metabolites required in later stages of the pathway.