Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 1, Problem 8PDQ
Describe the central dogma of molecular genetics and how it serves as the basis of modern genetics.
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Explain the concept of "Central Dogma of Molecular Biology"
Give at least three (3) importance of these tools in genetic engineering in the advancement of cell and molecular biology in the following fields:
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Increasingly, whole-genome sequencing of individuals is being done to help identify and treat medical conditions. Genome sequencing invariably identifies a number of variations, some common and some rare, that might be clinically relevant. For example, suppose a person had their genome sequenced to help determine their risk for cardiovascular disease and, just by chance, the sequence revealed that they carry one or more variants that predispose them to cancer or Alzheimer disease. Does the sequencing laboratory or physician have an obligation to report this finding, which was not the purpose of the sequencing and which the patient did not request? What about reporting variants for which no or limited information can be provided about their clinical significance? Does the answer to this question differ for sequencing done on children?
Chapter 1 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. 1 -
1. Describe Mendel’s conclusions about how...Ch. 1 -
2. Review the Chapter Concepts list on p. 1....Ch. 1 - What is the chromosome theory of inheritance, and...Ch. 1 - Prob. 4PDQCh. 1 -
5. Given the state of knowledge at the time of...Ch. 1 - Contrast chromosomes and genes.Ch. 1 - How is genetic information encoded in a DNA...Ch. 1 - Describe the central dogma of molecular genetics...Ch. 1 - How many different proteins, each with a unique...Ch. 1 - Outline the roles played by restriction enzymes...
Ch. 1 - What are some of the impacts of biotechnology on...Ch. 1 - Prob. 12PDQCh. 1 - We all carry about 20,000 genes in our genome. So...Ch. 1 - How has the use of model organisms advanced our...Ch. 1 - If you knew that a devastating late-onset...Ch. 1 -
16. Why do you think discoveries in genetics...
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- What is Central Dogma of Molecular Biology and how this concept is used in the development of genetically modified organisms?arrow_forwardWhat is the ultimate goal of genetic engineers, describe (in detail) the methods used to achieve this goal.arrow_forwardWhat are some possible research questions and practical applications that could be addressed by creating organisms with artificial chromosomes and synthetic genomes? What might be some potential safety, environmental, social, and ethical concerns about creating organisms with synthetic genomes?arrow_forward
- Describe several uses of genetic engineering in human medicine.arrow_forwardHerbert Boyer and Stanley Cohen pioneered the technique of DNA cloning allowing genes to be transferred from another biological species easily. Their work also gave rise to the development of different recombinant proteins with therapeutic applications like insulin and growth hormone. The former was cloned using Escherichia coli. coli in 1978. With this breakthrough, the first licensed drug produced using recombinant DNAtechnology was human insulin, developed by Genentech, licensed and marketed by Eli Lilly in 1982. Scientists were able to identify and isolate the gene fragment or the gene of interest, in this case, the gene that is responsible for producing insulin. Moreover, they were able to isolate the bacterial DNA of E. coli. The plasmid and DNA fragment were cut using a restriction enzyme. This DNA fragment was inserted into the plasmid using a DNA ligase. When the DNA fragment was then placed into the bacterial DNA, it was then introduced to the host cell (E. coli) and was then…arrow_forwardBriefly describe the components of the central dogma and give the importance of central dogma to geneticsarrow_forward
- Describe the impact of the 1953 publication of the Watson–Crick paper on genetic research?arrow_forwardDescribe the three basic goals of the Human Genome Project. What are at least three things we have learned from the project? Do you believe it was a worthwhile project? Why or why not?arrow_forwardLiving modified organism (LMO) is defined as any living organism that possesses a novel combination of genetic material obtained through the use of modern biotechnology. Two LMOs that have obtained approval from FDA to be commercialized are the Hawaiian 'Rainbow' papayas and the AquAdvantage salmons. Discuss the advantages of Hawaiian 'Rainbow' papayas and the AquAdvantage salmons over their respective wild type.arrow_forward
- I believe that there are many good things that can come out of people getting to design their baby’s genetic material. But there are also many bad things as well. From the article by Bio medical about the pros and cons of having a designer baby it states that a pro is that this type of engineering can “ might help prevent genetic diseases such as Alzheimer’s, Huntington’s Disease, down syndrome, Spinal Muscular Atrophy, and many others”. I think that it is great that we could get rid of Alzheimer’s due to how destructive it can be to the people that suffer it. But I think the other diseases that it can eliminate is horrible due to them making our world a more unique place such as people with autism, Down syndrome. By doing this it could eliminate the whole population of people with disabilities community and make everyone “normal”. Another bad that I found in the article Ethics of designer babies which states that a major flaw for these babies is “designer baby technologies suggest…arrow_forwardhttps://www.khanacademy.org/science/biology/biotech-dna-technology/dna-cloning-tutorial/a/overview-dna-cloning That is the link for the example ^arrow_forwardModel organisms are those widely used by researchers who wish to understand basic processes that are common to many species. Bacteria such as Escherichia coli are model organisms for modern geneticists. Give three reasons why bacteria would be useful in genetic experiments.arrow_forward
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