The propensity of mitochondrial disorders for encephalopathy rather than kidney and other disorders. Introduction: The ATP (adenosine triphosphate) production is vital for the functioning of the various systems and biochemical processes in the cell. The ATP can be generated through aerobic and anaerobic respiration. Several metabolic pathways like glycolysis, Kreb cycle, electron transport chain, alcohol fermentation and so on, generate ATP to power up the succeeding process.

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Chapter 1, Problem 4RE

A.

Summary Introduction

To determine: The propensity of mitochondrial disorders for encephalopathy rather than kidney and other disorders.

Introduction: The ATP (adenosine triphosphate) production is vital for the functioning of the various systems and biochemical processes in the cell. The ATP can be generated through aerobic and anaerobic respiration. Several metabolic pathways like glycolysis, Kreb cycle, electron transport chain, alcohol fermentation and so on, generate ATP to power up the succeeding process.

B.

Summary Introduction

To determine: The relative function of mitochondrial in terms of oxidative metabolism to develop lactic acidosis.

Introduction: Metabolic acidosis is the condition when there is accumulation of hydrogen ions inside the body due to inability of the body to remove excess hydrogen ions through excretory system which results in the decrease in the pH of the body fluids. This can occur due to loss of bicarbonate ions in diarrhea, type I diabetes, excess gastric acid secretion and many more.

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