The role of given investigation model in the events that shaped the history of life on the earth. Given: An experiment was conducted to evaluate the acclimatization and adaptability of bacteria on exposure to different treatment of antibiotics. The results are shown in the graph below: The figure shows the effects of the sudden, gradual, and moderate increase in antibiotics on the bacterial population. Introduction: The richness of earth species is a result of gradual evolution that led to the origin of basic single-celled prokaryotes to their evolution in complex multicellular organisms. On the other hand, sudden environmental changes led to massive effects on organisms likes the extinction of dinosaurs. A gradual environmental change often helps in adaptability of an organism.

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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q a) B1, b) B2, c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist f) t1/2,elim g) k10 h) k12 i) k21 j) initial concentration (C0) k) central compartment volume (V1) l) steady-state volume (Vss) m) clearance (CL) AUC (0→10 min) using trapezoidal rule n) AUC (20→30 min) using trapezoidal rule o) AUCtail (AUC360→∞) p) total AUC (using short cut method) q) volume from AUC (VAUC)

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Chapter 1, Problem 2Q

Summary Introduction

To analyze:

The role of given investigation model in the events that shaped the history of life on the earth.

Given:

An experiment was conducted to evaluate the acclimatization and adaptability of bacteria on exposure to different treatment of antibiotics. The results are shown in the graph below:

The figure shows the effects of the sudden, gradual, and moderate increase in antibiotics on the bacterial population.

Introduction:

The richness of earth species is a result of gradual evolution that led to the origin of basic single-celled prokaryotes to their evolution in complex multicellular organisms. On the other hand, sudden environmental changes led to massive effects on organisms likes the extinction of dinosaurs. A gradual environmental change often helps in adaptability of an organism.

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