The relation between MRS and ∆ G ˚ of the binding reaction. Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and interaction with taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

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Answer 1

Question

Chapter 1, Problem 16DAP

(a1)

Summary Introduction

To determine: The relation between MRS and ∆G˚ of the binding reaction.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and interaction with taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(a2)

Summary Introduction

To determine: Whether the more negative value of ∆G˚ will correspond to a higher or lower MRS.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet less. The sweetness is related to their structures and taste bud receptors on which the compounds bind. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(b)

Summary Introduction

To explain: The uses of predicting the sweetness of molecules by computer model instead of a human or animal-based taste assay.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. The assay that requires less time to generate valuable result would be convenient and desirable.

(c)

Summary Introduction

To determine: The AH-B groups in each of the given molecules when the length of a typical single bond is about 0.15 nm

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

(d)

Summary Introduction

To determine: The two objections to the statement that molecules containing an AH-B structure will taste sweet are to be determined.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

(e)

Summary Introduction

To determine: The two molecules out of given molecules that can be used to explain the difference in MRS and ∆G˚ and their relation to AH-B model.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(f)

Summary Introduction

To determine: The two examples that can be used to argue the AH-B model is unable to explain the observed differences in sweetness.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(g)

Summary Introduction

To determine: Whether need to test the model against a different set of molecules from the set it was trained on.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

(h)

Summary Introduction

To determine: The resulting error in MRS values as it has found that the predicted ∆G˚ values for the test set differed from the actual values by, on average, 1.3 kcal/mol.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

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Answer 2

Question

Chapter 1, Problem 16DAP

(a1)

Summary Introduction

To determine: The relation between MRS and ∆G˚ of the binding reaction.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and interaction with taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(a2)

Summary Introduction

To determine: Whether the more negative value of ∆G˚ will correspond to a higher or lower MRS.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet less. The sweetness is related to their structures and taste bud receptors on which the compounds bind. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(b)

Summary Introduction

To explain: The uses of predicting the sweetness of molecules by computer model instead of a human or animal-based taste assay.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. The assay that requires less time to generate valuable result would be convenient and desirable.

(c)

Summary Introduction

To determine: The AH-B groups in each of the given molecules when the length of a typical single bond is about 0.15 nm

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

(d)

Summary Introduction

To determine: The two objections to the statement that molecules containing an AH-B structure will taste sweet are to be determined.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

(e)

Summary Introduction

To determine: The two molecules out of given molecules that can be used to explain the difference in MRS and ∆G˚ and their relation to AH-B model.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(f)

Summary Introduction

To determine: The two examples that can be used to argue the AH-B model is unable to explain the observed differences in sweetness.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(g)

Summary Introduction

To determine: Whether need to test the model against a different set of molecules from the set it was trained on.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

(h)

Summary Introduction

To determine: The resulting error in MRS values as it has found that the predicted ∆G˚ values for the test set differed from the actual values by, on average, 1.3 kcal/mol.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

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Answer 3

Question

Chapter 1, Problem 16DAP

(a1)

Summary Introduction

To determine: The relation between MRS and ∆G˚ of the binding reaction.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and interaction with taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(a2)

Summary Introduction

To determine: Whether the more negative value of ∆G˚ will correspond to a higher or lower MRS.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet less. The sweetness is related to their structures and taste bud receptors on which the compounds bind. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(b)

Summary Introduction

To explain: The uses of predicting the sweetness of molecules by computer model instead of a human or animal-based taste assay.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. The assay that requires less time to generate valuable result would be convenient and desirable.

(c)

Summary Introduction

To determine: The AH-B groups in each of the given molecules when the length of a typical single bond is about 0.15 nm

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

(d)

Summary Introduction

To determine: The two objections to the statement that molecules containing an AH-B structure will taste sweet are to be determined.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

(e)

Summary Introduction

To determine: The two molecules out of given molecules that can be used to explain the difference in MRS and ∆G˚ and their relation to AH-B model.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(f)

Summary Introduction

To determine: The two examples that can be used to argue the AH-B model is unable to explain the observed differences in sweetness.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(g)

Summary Introduction

To determine: Whether need to test the model against a different set of molecules from the set it was trained on.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

(h)

Summary Introduction

To determine: The resulting error in MRS values as it has found that the predicted ∆G˚ values for the test set differed from the actual values by, on average, 1.3 kcal/mol.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

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Answer 4

Question

Chapter 1, Problem 16DAP

(a1)

Summary Introduction

To determine: The relation between MRS and ∆G˚ of the binding reaction.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and interaction with taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(a2)

Summary Introduction

To determine: Whether the more negative value of ∆G˚ will correspond to a higher or lower MRS.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet less. The sweetness is related to their structures and taste bud receptors on which the compounds bind. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(b)

Summary Introduction

To explain: The uses of predicting the sweetness of molecules by computer model instead of a human or animal-based taste assay.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. The assay that requires less time to generate valuable result would be convenient and desirable.

(c)

Summary Introduction

To determine: The AH-B groups in each of the given molecules when the length of a typical single bond is about 0.15 nm

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

(d)

Summary Introduction

To determine: The two objections to the statement that molecules containing an AH-B structure will taste sweet are to be determined.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

(e)

Summary Introduction

To determine: The two molecules out of given molecules that can be used to explain the difference in MRS and ∆G˚ and their relation to AH-B model.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(f)

Summary Introduction

To determine: The two examples that can be used to argue the AH-B model is unable to explain the observed differences in sweetness.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(g)

Summary Introduction

To determine: Whether need to test the model against a different set of molecules from the set it was trained on.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

(h)

Summary Introduction

To determine: The resulting error in MRS values as it has found that the predicted ∆G˚ values for the test set differed from the actual values by, on average, 1.3 kcal/mol.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

Expert Solution & Answer

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See solution

Answer 5

Chapter 1, Problem 16DAP

(a1)

Summary Introduction

To determine: The relation between MRS and ∆G˚ of the binding reaction.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and interaction with taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(a2)

Summary Introduction

To determine: Whether the more negative value of ∆G˚ will correspond to a higher or lower MRS.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet less. The sweetness is related to their structures and taste bud receptors on which the compounds bind. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(b)

Summary Introduction

To explain: The uses of predicting the sweetness of molecules by computer model instead of a human or animal-based taste assay.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. The assay that requires less time to generate valuable result would be convenient and desirable.

(c)

Summary Introduction

To determine: The AH-B groups in each of the given molecules when the length of a typical single bond is about 0.15 nm

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

(d)

Summary Introduction

To determine: The two objections to the statement that molecules containing an AH-B structure will taste sweet are to be determined.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

(e)

Summary Introduction

To determine: The two molecules out of given molecules that can be used to explain the difference in MRS and ∆G˚ and their relation to AH-B model.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(f)

Summary Introduction

To determine: The two examples that can be used to argue the AH-B model is unable to explain the observed differences in sweetness.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

(g)

Summary Introduction

To determine: Whether need to test the model against a different set of molecules from the set it was trained on.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

(h)

Summary Introduction

To determine: The resulting error in MRS values as it has found that the predicted ∆G˚ values for the test set differed from the actual values by, on average, 1.3 kcal/mol.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

Answer 6

Chapter 1, Problem 16DAP

(a1)

Summary Introduction

To determine: The relation between MRS and ∆G˚ of the binding reaction.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and interaction with taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

Answer 7

Chapter 1, Problem 16DAP

(a1)

Summary Introduction

To determine: The relation between MRS and ∆G˚ of the binding reaction.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and interaction with taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

Answer 8

(a2)

Summary Introduction

To determine: Whether the more negative value of ∆G˚ will correspond to a higher or lower MRS.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet less. The sweetness is related to their structures and taste bud receptors on which the compounds bind. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

Answer 9

(a2)

Summary Introduction

To determine: Whether the more negative value of ∆G˚ will correspond to a higher or lower MRS.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet less. The sweetness is related to their structures and taste bud receptors on which the compounds bind. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

Answer 10

(b)

Summary Introduction

To explain: The uses of predicting the sweetness of molecules by computer model instead of a human or animal-based taste assay.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. The assay that requires less time to generate valuable result would be convenient and desirable.

Answer 11

(b)

Summary Introduction

To explain: The uses of predicting the sweetness of molecules by computer model instead of a human or animal-based taste assay.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. The assay that requires less time to generate valuable result would be convenient and desirable.

Answer 12

(c)

Summary Introduction

To determine: The AH-B groups in each of the given molecules when the length of a typical single bond is about 0.15 nm

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

Answer 13

(c)

Summary Introduction

To determine: The AH-B groups in each of the given molecules when the length of a typical single bond is about 0.15 nm

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

Answer 14

(d)

Summary Introduction

To determine: The two objections to the statement that molecules containing an AH-B structure will taste sweet are to be determined.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

Answer 15

(d)

Summary Introduction

To determine: The two objections to the statement that molecules containing an AH-B structure will taste sweet are to be determined.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

Answer 16

(e)

Summary Introduction

To determine: The two molecules out of given molecules that can be used to explain the difference in MRS and ∆G˚ and their relation to AH-B model.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

Answer 17

(e)

Summary Introduction

To determine: The two molecules out of given molecules that can be used to explain the difference in MRS and ∆G˚ and their relation to AH-B model.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

Answer 18

(f)

Summary Introduction

To determine: The two examples that can be used to argue the AH-B model is unable to explain the observed differences in sweetness.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

Answer 19

(f)

Summary Introduction

To determine: The two examples that can be used to argue the AH-B model is unable to explain the observed differences in sweetness.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

Answer 20

(g)

Summary Introduction

To determine: Whether need to test the model against a different set of molecules from the set it was trained on.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

Answer 21

(g)

Summary Introduction

To determine: Whether need to test the model against a different set of molecules from the set it was trained on.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

Answer 22

(h)

Summary Introduction

To determine: The resulting error in MRS values as it has found that the predicted ∆G˚ values for the test set differed from the actual values by, on average, 1.3 kcal/mol.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

Answer 23

(h)

Summary Introduction

To determine: The resulting error in MRS values as it has found that the predicted ∆G˚ values for the test set differed from the actual values by, on average, 1.3 kcal/mol.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors. Molar relative sweetness (MRS) is the measure of sweetness of the compound relative to sweetness of sucrose.

Answer 24

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Answer 26

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Answer 27

Ch. 1 - Prob. 1P Ch. 1 - Prob. 2P Ch. 1 - Prob. 3P Ch. 1 - Prob. 4P Ch. 1 - Prob. 5P Ch. 1 - Prob. 6P Ch. 1 - Prob. 7P Ch. 1 - Prob. 8P Ch. 1 - Prob. 9P Ch. 1 - Prob. 10P

Concept explainers

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To determine: The AH-B groups in each of the given molecules when the length of a typical single bond is about 0.15 nm

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

To determine: Whether need to test the model against a different set of molecules from the set it was trained on.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

Want to see the full answer?

Chapter 1 Solutions

Concept explainers

Videos

To determine: The AH-B groups in each of the given molecules when the length of a typical single bond is about 0.15 nm Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

To determine: Whether need to test the model against a different set of molecules from the set it was trained on. Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

Want to see the full answer?

Chapter 1 Solutions

To determine: The AH-B groups in each of the given molecules when the length of a typical single bond is about 0.15 nm

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.

To determine: Whether need to test the model against a different set of molecules from the set it was trained on.

Introduction: Various compounds taste sweet. Some of them sweet more, while some of them sweet lesser. The sweetness is related to their structures and taste bud receptors.