Biological Science, Books a la Carte Plus Mastering Biology with Pearson eText -- Access Card Package (6th Edition)
Biological Science, Books a la Carte Plus Mastering Biology with Pearson eText -- Access Card Package (6th Edition)
6th Edition
ISBN: 9780134296029
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
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Chapter 1, Problem 10TYPSS
Summary Introduction

To review:

The human populations would likely evolve differently in areas of the world where HIV infection rates are high.

Introduction:

The genes (heritable traits) are passed from the parents to their offspring. The traits give identity to an individual. Few traits are required for the survival. Some genes undergo evolution for the better survival of the individual. The individuals with evolved traits produce offspring having the same traits. Thus, the frequency of such traits increases in a population and this leads to evolution.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.
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