7.You want to study the effect of lysine methylation on gene regulation. The lysine aminoacid sidechain is -CH2CH2CH2CH2NH2. To begin to study the relevant functional groups,you take free CH3CH2CH2CH2NH2 in the lab and decide to try to turn it into the product(P) CH3CH2CH2CH2NHCH3.a) Suggest a simple reagent to carry out the desired transformation. (In thesubsequent parts of the problem, you may call this reagent R for short).b) Draw the reaction using the arrow formalism.c) What solvent and pH do you suggest? Why?d) Is the reaction first order or second order?e) Write down a simple rate equation for dP/dt. If you include any constant(s), whatare their units?f) In addition to the desired product P, name at least one other impurity (containingboth carbon and nitrogen, you may call this compound U for short) that is likely tooccur in substantial amounts.g) What choice of initial conditions would bias towards production of substantiallymore P than U?

The objective of this question os to explain the lysine methylation on gene regulation. It mainly…

You want to study the effect of lysine methylation on gene regulation. The lysine amino acid sidechain is-CH2CH2CH2CH2NH2. To begin to study the relevant functional groups, you take free CH3CH2CH2CH2NH2 in the lab and decide to try to turn it into the product (P) CH3CH2CH2CH2NHCH3. a) Suggest a simple reagent to carry out the desired transformation. (In the subsequent parts of the problem, you may call this reagent R for short). Draw the reaction using the arrow formalism. b) c) What solvent and pH do you suggest? Why? d) Is the reaction first order or second order? e) Write down a simple rate equation for dP/dt. If you include any constant(s), what are their units? f) In addition to the desired product P, name at least one other impurity (containing both carbon and nitrogen, you may call this compound U for short) that is likely to occur in substantial amounts. g) What choice of initial conditions would bias towards production of substantially more P than U?

You want to study the effect of lysine methylation on gene regulation. The lysine amino acid sidechain is-CH2CH2CH2CH2NH2. To begin to study the relevant functional groups, you take free CH3CH2CH2CH2NH2 in the lab and decide to try to turn it into the product (P) CH3CH2CH2CH2NHCH3. a) Suggest a simple reagent to carry out the desired transformation. (In the subsequent parts of the problem, you may call this reagent R for short). Draw the reaction using the arrow formalism. b) c) What solvent and pH do you suggest? Why? d) Is the reaction first order or second order? e) Write down a simple rate equation for dP/dt. If you include any constant(s), what are their units? f) In addition to the desired product P, name at least one other impurity (containing both carbon and nitrogen, you may call this compound U for short) that is likely to occur in substantial amounts. g) What choice of initial conditions would bias towards production of substantially more P than U?

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Question

7.
You want to study the effect of lysine methylation on gene regulation. The lysine amino
acid sidechain is -CH2CH2CH2CH2NH2. To begin to study the relevant functional groups,
you take free CH3CH2CH2CH2NH2 in the lab and decide to try to turn it into the product
(P) CH3CH2CH2CH2NHCH3.
a) Suggest a simple reagent to carry out the desired transformation. (In the
subsequent parts of the problem, you may call this reagent R for short).
b) Draw the reaction using the arrow formalism.
c) What solvent and pH do you suggest? Why?
d) Is the reaction first order or second order?
e) Write down a simple rate equation for dP/dt. If you include any constant(s), what
are their units?
f) In addition to the desired product P, name at least one other impurity (containing
both carbon and nitrogen, you may call this compound U for short) that is likely to
occur in substantial amounts.
g) What choice of initial conditions would bias towards production of substantially
more P than U?

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