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You have just been hired to deliver DNA test results to Maury on the Maury show. The mother and child have returned for the 3rd time to try and determine who the father of the child is. After Maury has a discussion with the mother and alleged father it is time for the results! You hand Maury the envelope with the paternity analysis results. But wait, there is a problem. The results have not been analyzed, and Maury has no idea how to read them. You quickly jump into action to interpret the results. View the results below and determine if this is the father of the child by comparing the tested allele sizes to each other. Remember that the alleles in the offspring must come from either the mother or father. The results map known genes and indicate the size of each allele from the two chromosomes of the child. If only one size is listed, then they are homozygous for that gene, if there are two then they are heterozygous. DNA Test Report DOC351505 Case 7514997 CHILD Alleged FATHER Name Test No. 7514997-20 7514997-30 Allele Sues Locus PI Alele Sizes 17 17 14 03S1358 DISI656 D25441 D1OS 1248 0.83 D135317 Penta E D165539 D18851 D281338 CSF IPO Penta D TH0I WA 16 16 10 13 18 16.3 14 14 10 0.00 0.00 18.3 1.93 14 16 0.00 0.00 0.00 11 15 13 14 10 12 17 0.00 0.00 0.00 1.12 1.04 13 14 10 0.00 31.2 021811 D7S820 322 11 0.00 0.00 0.67 D55818 12 TPOX 1.86 DES1 179 D128301 D198433 FGA 0225 1045 0.00 Amelogenin 12 19 14.2 24 16 0.00 18 0.00 0.00 4.13 20.2 11 Determine if this is the father and explain your conclusion.

You have just been hired to deliver DNA test results to Maury on the Maury show. The mother and child have returned for the 3rd time to try and determine who the father of the child is. After Maury has a discussion with the mother and alleged father it is time for the results! You hand Maury the envelope with the paternity analysis results. But wait, there is a problem. The results have not been analyzed, and Maury has no idea how to read them. You quickly jump into action to interpret the results. View the results below and determine if this is the father of the child by comparing the tested allele sizes to each other. Remember that the alleles in the offspring must come from either the mother or father. The results map known genes and indicate the size of each allele from the two chromosomes of the child. If only one size is listed, then they are homozygous for that gene, if there are two then they are heterozygous. DNA Test Report DOC351505 Case 7514997 CHILD Alleged FATHER Name Test No. 7514997-20 7514997-30 Allele Sues Locus PI Alele Sizes 17 17 14 03S1358 DISI656 D25441 D1OS 1248 0.83 D135317 Penta E D165539 D18851 D281338 CSF IPO Penta D TH0I WA 16 16 10 13 18 16.3 14 14 10 0.00 0.00 18.3 1.93 14 16 0.00 0.00 0.00 11 15 13 14 10 12 17 0.00 0.00 0.00 1.12 1.04 13 14 10 0.00 31.2 021811 D7S820 322 11 0.00 0.00 0.67 D55818 12 TPOX 1.86 DES1 179 D128301 D198433 FGA 0225 1045 0.00 Amelogenin 12 19 14.2 24 16 0.00 18 0.00 0.00 4.13 20.2 11 Determine if this is the father and explain your conclusion.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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**Educational Transcription: DNA Test Report Interpretation** **Scenario:** You've been tasked with interpreting DNA test results for a segment on the Maury show, where the goal is to determine the paternity of a child. The results need clarification and explanation. **DNA Test Report Analysis:** **Case Number:** 7514997 The report details alleles at various loci for both the child and the alleged father. Below is a summary of the genetic information provided: | **Locus** | **Child Allele Sizes** | **Alleged Father Allele Sizes** | |--------------|------------------------|---------------------------------| | D3S1358 | 16 | 16, 18.3 | | D16S539 | 11, 12 | 11, 12 | | D18S51 | 17 | 17, 14.3 | | D5S818 | 11, 13 | 11, 13 | | D21S11 | 29 | 28, 29 | | D7S820 | 10, 12 | 10, 12 | | CSF1PO | 11, 12 | 11, 12 | | FGA | 240 | 240, 250 | **Interpretation Guidelines:** - Alleles must match between the child and the alleged father at each locus for paternity to be confirmed. - Only one allele has to match the child’s allele size at each locus. **Conclusion:** By examining the alleles, all loci show at least one matching allele size between the child and the alleged father. This consistent match across all loci strongly suggests that the alleged father is indeed the biological father of the child.
Transcribed Image Text:**Educational Transcription: DNA Test Report Interpretation** **Scenario:** You've been tasked with interpreting DNA test results for a segment on the Maury show, where the goal is to determine the paternity of a child. The results need clarification and explanation. **DNA Test Report Analysis:** **Case Number:** 7514997 The report details alleles at various loci for both the child and the alleged father. Below is a summary of the genetic information provided: | **Locus** | **Child Allele Sizes** | **Alleged Father Allele Sizes** | |--------------|------------------------|---------------------------------| | D3S1358 | 16 | 16, 18.3 | | D16S539 | 11, 12 | 11, 12 | | D18S51 | 17 | 17, 14.3 | | D5S818 | 11, 13 | 11, 13 | | D21S11 | 29 | 28, 29 | | D7S820 | 10, 12 | 10, 12 | | CSF1PO | 11, 12 | 11, 12 | | FGA | 240 | 240, 250 | **Interpretation Guidelines:** - Alleles must match between the child and the alleged father at each locus for paternity to be confirmed. - Only one allele has to match the child’s allele size at each locus. **Conclusion:** By examining the alleles, all loci show at least one matching allele size between the child and the alleged father. This consistent match across all loci strongly suggests that the alleged father is indeed the biological father of the child.
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