An STR on chromosome 9 is immediately adjacent to a gene involved in a dominant blood disorder (only one copy of the mutation is required for the disease). Thus, in a family with a known mutation in the disorder-causing gene, inheritance of the STR can be used to diagnose the disorder. There are four different alleles of the STR (A, B, C and D), each with different numbers of GATCTCG repeats. The A allele has 10 repeats, the B allele has 19 repeats, the Callele has 25 repeats, and the D allele has 13 repeats. Lane 1 Janavi Mehmet Prita Kamu Ravi Shreeta Part 3 Why does Kamu have only one band on the gel? BI U A I E E E| x x, = E Paragraph 14pt fr

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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An STR on chromosome 9 is immediately adjacent to a gene involved in a dominant blood disorder (only one copy of the mutation is required for the disease). Thus, in a family
with a known mutation in the disorder-causing gene, inheritance of the STR can be used to diagnose the disorder. There are four different alleles of the STR (A, B, C and D), each
with different numbers of GATCTCG repeats. The A allele has 10 repeats, the B allele has 19 repeats, the Callele has 25 repeats, and the D allele has 13 repeats.
Transcribed Image Text:An STR on chromosome 9 is immediately adjacent to a gene involved in a dominant blood disorder (only one copy of the mutation is required for the disease). Thus, in a family with a known mutation in the disorder-causing gene, inheritance of the STR can be used to diagnose the disorder. There are four different alleles of the STR (A, B, C and D), each with different numbers of GATCTCG repeats. The A allele has 10 repeats, the B allele has 19 repeats, the Callele has 25 repeats, and the D allele has 13 repeats.
Lane 1
Janavi Mehmet
Prita
Kamu
Ravi
Shreeta
Part 3
Why does Kamu have only one band on the gel?
BI U
A
I E E E| x x, = E
Paragraph
14pt
fr
Transcribed Image Text:Lane 1 Janavi Mehmet Prita Kamu Ravi Shreeta Part 3 Why does Kamu have only one band on the gel? BI U A I E E E| x x, = E Paragraph 14pt fr
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