You are working for a drug discovery company. Your team has identified a derivative (you will be given a randomly elected compound from the table below) of aspirin/ paracetamol, has optimal physicochemical properties for biological activity. To conduct preliminary tests on the drug candidate you are required to synthesise the derivative from benzene. Propose a synthetic pathway starting from benzene to the candidate drug.Important: your company wants efficiency, a ynthetic, pathways that provide good yield (major product) and are energy efficient (if possible, avoid pathways that mvolve working with lots of ring deactivating groups) is Br OH

Chemistry
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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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You are working for a drug discovery company. Your team has identified a derivative (you will be given a randomly
selected compound from the table below) of aspirin/ paracetamol, has optimal physicochemical properties for biological
activity. To conduct preliminary tests on the drug candidate you are required to synthesise the derivative from benzene.
Propose a synthetic pathway starting from benzene to the candidate drug. Important: your company wants efficiency, a
synthetic, pathways that provide good yield (major product) and are energy efficient (if possible, avoid pathways that
involve working with lots of ring deactivating groups) is
Br
OH
Transcribed Image Text:You are working for a drug discovery company. Your team has identified a derivative (you will be given a randomly selected compound from the table below) of aspirin/ paracetamol, has optimal physicochemical properties for biological activity. To conduct preliminary tests on the drug candidate you are required to synthesise the derivative from benzene. Propose a synthetic pathway starting from benzene to the candidate drug. Important: your company wants efficiency, a synthetic, pathways that provide good yield (major product) and are energy efficient (if possible, avoid pathways that involve working with lots of ring deactivating groups) is Br OH
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