You are studying an E. coli gene that specifies a protein. A part of its sequence is–Ala–Pro–Trp–Ser–Glu–Lys–Cys–His–You recover a series of mutants for this gene that show no enzymatic activity. By isolating the mutant enzyme products, you find the following sequences:Mutant 1:–Ala–Pro–Trp–Arg–Glu–Lys–Cys–His–Mutant 2:–Ala–Pro–Mutant 3:–Ala–Pro–Gly–Val–Lys–Asn–Cys–His–Mutant 4:–Ala–Pro–Trp–Phe–Phe–Thr–Cys–His–What is the molecular basis for each mutation? What is the DNA sequence that specifies this part of the protein?
You are studying an E. coli gene that specifies a protein. A part of its sequence is–Ala–Pro–Trp–Ser–Glu–Lys–Cys–His–You recover a series of mutants for this gene that show no enzymatic activity. By isolating the mutant enzyme products, you find the following sequences:Mutant 1:–Ala–Pro–Trp–Arg–Glu–Lys–Cys–His–Mutant 2:–Ala–Pro–Mutant 3:–Ala–Pro–Gly–Val–Lys–Asn–Cys–His–Mutant 4:–Ala–Pro–Trp–Phe–Phe–Thr–Cys–His–What is the molecular basis for each mutation? What is the DNA sequence that specifies this part of the protein?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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You are studying an E. coli gene that specifies a protein. A
part of its sequence is
–Ala–Pro–Trp–Ser–Glu–Lys–Cys–His–
You recover a series of mutants for this gene that show
no enzymatic activity. By isolating the mutant enzyme
products, you find the following sequences:
Mutant 1:
–Ala–Pro–Trp–Arg–Glu–Lys–Cys–His–
Mutant 2:
–Ala–Pro–
Mutant 3:
–Ala–Pro–Gly–Val–Lys–Asn–Cys–His–
Mutant 4:
–Ala–Pro–Trp–Phe–Phe–Thr–Cys–His–
What is the molecular basis for each mutation? What is
the DNA sequence that specifies this part of the protein?
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