You are studying a biochemical pathway that requires ATP as an energy source. To your dismay, the reactions soon stop, partly because the ATP is rapidly used up and partly because an excess of ADP builds up and inhibits the enzymes involved. You are about to give up when the following table from a biochemistry textbook catches your eye creatine+ ATP → creatine phosphate + ADP; AG (+)3 kcal / mol ATP + H₂O → ADP + phosphate; AG = (-)7.3 kcal / mol Glucose-6-phosphate + H₂O → glucose + phosphate; AG= (-)3.3 kcal/mol What is about these equations that provides a solution to your problem? If you add enough creatine, ATP will be regenerated If you add enough ADP, ATP will be regenerated If you supply creatine phosphate, ADP will be depleted and more ATP produced. This will allow your reactions to continue Supplying glucose-6-phosphate will provide enough free phosphate to regenerate ATP

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You are studying a biochemical pathway that requires ATP as an energy source. To
your dismay, the reactions soon stop, partly because the ATP is rapidly used up and
partly because an excess of ADP builds up and inhibits the enzymes involved. You
are about to give up when the following table from a biochemistry textbook catches
your eye
creatine + ATP →→ creatine phosphate + ADP; AG (+)3 kcal / mol
ATP + H₂O → ADP + phosphate; AG = (-)7.3 kcal / mol
Glucose-6-phosphate + H₂O → glucose + phosphate; AG= (-)3.3 kcal/mol
What is about these equations that provides a solution to your problem?
If you add enough creatine, ATP will be regenerated
If you add enough ADP, ATP will be regenerated
If you supply creatine phosphate, ADP will be depleted and more ATP produced.
This will allow your reactions to continue
Supplying glucose-6-phosphate will provide enough free phosphate to
regenerate ATP
On the basis of the two reactions below, indicate whether the following statements are TRUE or
FALSE.
1: ATP+YY-P+ ADP AG -100 kcal/mole
2: Y-P+A B
AG -50 kcal/mole
DO
Reaction 1 is favorable
because of the large
negative AG associated
with the hydrolysis of ATP.
Reaction 2 is an example of
an unfavorable reaction.
Reaction 2 can be used to
drive reaction 1 in the
reverse direction.
F
Reactions 1 and 2 are
coupled reactions, and
when they take place
together, reaction 2 will
proceed in the forward
direction.
1. True
2. False
Transcribed Image Text:You are studying a biochemical pathway that requires ATP as an energy source. To your dismay, the reactions soon stop, partly because the ATP is rapidly used up and partly because an excess of ADP builds up and inhibits the enzymes involved. You are about to give up when the following table from a biochemistry textbook catches your eye creatine + ATP →→ creatine phosphate + ADP; AG (+)3 kcal / mol ATP + H₂O → ADP + phosphate; AG = (-)7.3 kcal / mol Glucose-6-phosphate + H₂O → glucose + phosphate; AG= (-)3.3 kcal/mol What is about these equations that provides a solution to your problem? If you add enough creatine, ATP will be regenerated If you add enough ADP, ATP will be regenerated If you supply creatine phosphate, ADP will be depleted and more ATP produced. This will allow your reactions to continue Supplying glucose-6-phosphate will provide enough free phosphate to regenerate ATP On the basis of the two reactions below, indicate whether the following statements are TRUE or FALSE. 1: ATP+YY-P+ ADP AG -100 kcal/mole 2: Y-P+A B AG -50 kcal/mole DO Reaction 1 is favorable because of the large negative AG associated with the hydrolysis of ATP. Reaction 2 is an example of an unfavorable reaction. Reaction 2 can be used to drive reaction 1 in the reverse direction. F Reactions 1 and 2 are coupled reactions, and when they take place together, reaction 2 will proceed in the forward direction. 1. True 2. False
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