Yo₂ 1.0 0.8 0.6 0.4 0.2 0 Weak-binding 20 Transition from weak- to strong-binding Strong-binding 40 60 80 Po, (mm Hg) 100 120 Use the oxygen binding curve to complete the information about data points at various sites in the graph. Match the words in the left column to the appropriate blanks in the sentences on the right.

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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7l.3.3

### Oxygen Binding Curve Analysis

The graph presented is an oxygen binding curve, illustrating the relationship between the partial pressure of oxygen (\(P_{O_2}\)) in mm Hg and the fractional saturation of hemoglobin (\(Y_{O_2}\)).

#### Graph Description

- **X-Axis**: Represents the partial pressure of oxygen (\(P_{O_2}\)) in mm Hg, ranging from 0 to 120 mm Hg.
- **Y-Axis**: Represents the fractional saturation of hemoglobin (\(Y_{O_2}\)), which ranges from 0 to 1.0.

#### Binding Regions

1. **Weak-binding Region**: At lower partial pressures (\(0 - 20 \, \text{mm Hg}\)), saturation levels are low, indicating weak binding.
2. **Transition Region**: Between approximately 20 and 60 mm Hg, there is a sharp increase in saturation, marking a transition from weak to strong binding.
3. **Strong-binding Region**: At higher partial pressures (\(60 - 120 \, \text{mm Hg}\)), saturation approaches maximum levels, indicating strong binding.

### Comprehension Exercise

Match the terms from the left column (saturation ranges and pressure ranges) to the corresponding blanks in the sentences on the right.

#### Phrases to Complete:

1. **Partial Pressure and Saturation**:
   - When the environment is a system with a partial pressure of oxygen at 10 mm Hg, the approximate fractional saturation of hemoglobin is between **0.0 to 0.2**.

2. **Lung and Tissue Saturation**:
   - The approximate fractional saturation of hemoglobin when it is near the lungs is **0.8 to 1.0** and when it is near the resting tissues, the approximate fractional saturation is **0.4 to 0.6**.

3. **Oxygen Pressure Levels**:
   - The approximate partial pressure of oxygen is **20 to 40 mm Hg** when oxygen has bound 50% of the available hemoglobin binding sites, and is **60 to 80 mm Hg** when oxygen has bound 90% of the available hemoglobin binding sites.
Transcribed Image Text:### Oxygen Binding Curve Analysis The graph presented is an oxygen binding curve, illustrating the relationship between the partial pressure of oxygen (\(P_{O_2}\)) in mm Hg and the fractional saturation of hemoglobin (\(Y_{O_2}\)). #### Graph Description - **X-Axis**: Represents the partial pressure of oxygen (\(P_{O_2}\)) in mm Hg, ranging from 0 to 120 mm Hg. - **Y-Axis**: Represents the fractional saturation of hemoglobin (\(Y_{O_2}\)), which ranges from 0 to 1.0. #### Binding Regions 1. **Weak-binding Region**: At lower partial pressures (\(0 - 20 \, \text{mm Hg}\)), saturation levels are low, indicating weak binding. 2. **Transition Region**: Between approximately 20 and 60 mm Hg, there is a sharp increase in saturation, marking a transition from weak to strong binding. 3. **Strong-binding Region**: At higher partial pressures (\(60 - 120 \, \text{mm Hg}\)), saturation approaches maximum levels, indicating strong binding. ### Comprehension Exercise Match the terms from the left column (saturation ranges and pressure ranges) to the corresponding blanks in the sentences on the right. #### Phrases to Complete: 1. **Partial Pressure and Saturation**: - When the environment is a system with a partial pressure of oxygen at 10 mm Hg, the approximate fractional saturation of hemoglobin is between **0.0 to 0.2**. 2. **Lung and Tissue Saturation**: - The approximate fractional saturation of hemoglobin when it is near the lungs is **0.8 to 1.0** and when it is near the resting tissues, the approximate fractional saturation is **0.4 to 0.6**. 3. **Oxygen Pressure Levels**: - The approximate partial pressure of oxygen is **20 to 40 mm Hg** when oxygen has bound 50% of the available hemoglobin binding sites, and is **60 to 80 mm Hg** when oxygen has bound 90% of the available hemoglobin binding sites.
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