Write the main products of the synthesis reaction according to the specified raw materials, reagents and reaction conditions.. OH H3PO4 / BF3 • OEl (1) Br Br CH3LI (2) ether NO2 CH,Br RNH2 (3) EtNMeOH CO,CH3 OCH3 OMs O Ph- H2NNH2 • H2O EIOH, 60°C DMF (4) HN DABCO, DMF (5) `NH2
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
![Write the main products of the synthesis reaction
according to the specified raw
materials, reagents and reaction conditions..
OH
H3PO4 / BF3 OEt,
(1)
Br
Br
CH3LI
ether
(2)
NO2
CH2Br
RNH2
(3)
ElgN/MEOH
CO2CH3
OCH3
OMs
:0 Ph
DMF
H2NNH2 • H2O
(4)
HN
E1OH, 60°C
DABCO, DMF
(5)
NH2](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F9ba75ae4-5fca-43ee-bb8c-9e36bd6df409%2Fa0914367-8f5e-4b41-9faf-347482a281df%2Fu481uhq_processed.jpeg&w=3840&q=75)
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