work. 7) Some amino acids are considered glucogenic, other ketogenic and some as both. What do these terms mean and what does it mean for an amino acid to be both? 8) Would the
work. 7) Some amino acids are considered glucogenic, other ketogenic and some as both. What do these terms mean and what does it mean for an amino acid to be both? 8) Would the
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
Number 7

Transcribed Image Text:6) Briefly summarize the findings of Rudolf Schoenheimer's work in amino acid metabolism. Include
at least 3 different significant results or inferences from his work.
7) Some amino acids are considered glucogenic, other ketogenic and some as both. What do these
terms mean and what does it mean for an amino acid to be both?
8) Would the tetrapeptide W-X-Y-Z have the same pl as a peptide Z-Y-X-W? Why or why not?
Nonpolar Aliphatic Amino Acids
CH3
CH,
H&C
H,C -
CH3
H.
CH3
CH3
H.
COO®
Alanine (Ala; A)
coo®
COOe
H,N
Isoleucine (lle; I)
COO®
H,N
Glycine (Gly; G)
HgN
Leucine (Leu; L)
COOe
Valine (Val; V)
Nonpolar Aromatic Amino Acids
но
Nonpolar Amino Acids
CH3
S
HN
H
H.
COO
H,N
COOe
N.
COoe
H,N°
COOe
HgN
Proline (Pro; P)
Methionine (Met; M)
Phenylalanine (Phe; F)
Tyrosine (Tyr; Y)
Tryptophan (Trp; W)
Expert Solution

Step 1
Amino acids polymerize to form polypeptides. From the 20 standard amino acids that are incorporated into proteins, there are 8 essential amino acids that are synthesized in the body and 12 non-essential amino acids that are derived through diet. The non-essential amino acids are synthesized from intermediates of the TCA cycle, glycolysis, and the pentose phosphate pathway. The intermediates used are glycerate-3-phosphate, pyruvate, α-ketoglutarate, oxaloacetate, ribose-5-phosphate, phosphoenolpyruvate, and erythrose-4-phosphate.
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