Why is aneuploidy of the sex chromosomes less debilitating than aneuploidy of even the smallest autosomes?(Note: multiple responses are correct, please choose the best answer(s))Select one or more:Only one X chromosome is required at any given time. Additional X chromosomes (as in females) are inactivated in most cells except for gametesDosage compensation requires that all excess chromosomes (i.e. 2 or more) are activated at all times during the cell cycleThe Y chromosome carries a number of critical genes involved in spermatogenesis and sex development. Therefore, having two copies of the Y chromosome results in the overproduction of sperm and increased fertilityThe Y chromosome carries a number of critical genes required for spermatogenesis and sex development, but very few other genes. Therefore, having two copies of the Y chromosome has minimal impact on the balance of gene expression

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Description: Why is aneuploidy of the sex chromosomes less debilitating than aneuploidy of even the smallest autosomes?(Note: multiple responses are correct, please choose the best answer(s))Select one or more:Only one X chromosome is required at any given time.

Aneuploidy is the condition in which there is an abnormality in chromosome number in a cell. Healthy…

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Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

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Why is aneuploidy of the sex chromosomes less debilitating than aneuploidy of even the smallest autosomes?

(Note: multiple responses are correct, please choose the best answer(s))

Select one or more:

Only one X chromosome is required at any given time. Additional X chromosomes (as in females) are inactivated in most cells except for gametes

Dosage compensation requires that all excess chromosomes (i.e. 2 or more) are activated at all times during the cell cycle

The Y chromosome carries a number of critical genes involved in spermatogenesis and sex development. Therefore, having two copies of the Y chromosome results in the overproduction of sperm and increased fertility

The Y chromosome carries a number of critical genes required for spermatogenesis and sex development, but very few other genes. Therefore, having two copies of the Y chromosome has minimal impact on the balance of gene expression

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