Answered: Why does reversible chain termination…

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter11: Genome Alterations: Mutation And Epigenetics

Section: Chapter Questions

Problem 12QP

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Why does reversible chain termination sequencing yield short reads?

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In genetics, sequencing is considered a methodology to determine the order of nucleotides(adenine, guanine, cytosine, and thymine) in DNA, which helps in identifying the proteins they encode and the diseases caused by any alteration in the nucleotides.

Reversible terminator sequencing is considered a modified nucleotide analogous in sequencing, which is used to terminate primer extension reversibly.

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