Which of these experiments sounds the most like it would be analyzed with an Independent-Samples t-test?

MATLAB: An Introduction with Applications
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Which of these experiments sounds the most like it would be analyzed with an Independent-Samples t-test?

A. A study that gives patients a placebo on Monday and measures their pain, then has them back on Friday and gives them a real pain pill and measures their pain
 
B. A study that compares tennis players vs. football players on their peak heart rate while playing their sports
 
C.A study that looks at the attention span of a group of n=30 5-year-olds and then follows up with those same kids when they are 10-years-old
 
D. A study that measures the knowledge of the transfer process for a group of Chaffey students, both before and after they attend an orientation
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