Which of the following statements best describe(s) the mechanism by which correct protein folding takes place once the misfolded protein binds the open ring of

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Which of the following statements best
describe(s) the mechanism by which correct
protein folding takes place once the
misfolded protein binds the open ring of
groEL? Select all that apply.
The groEL ring closes to isolate the protein and provide enough
time for the protein to properly fold on its own.
b and d
The groEL ring closes to provide a hydrophilic space to isolate
the protein and inhibit its aggregation with others until properly
folded.
The groEL ring closes to isolate the protein and provide steric
hindrance that mechanically refolds the protein.
The groEL ring closes to isolate the protein and decode the
information necessary to achieve the correct three-dimensional
structure.
None of the above
Transcribed Image Text:Which of the following statements best describe(s) the mechanism by which correct protein folding takes place once the misfolded protein binds the open ring of groEL? Select all that apply. The groEL ring closes to isolate the protein and provide enough time for the protein to properly fold on its own. b and d The groEL ring closes to provide a hydrophilic space to isolate the protein and inhibit its aggregation with others until properly folded. The groEL ring closes to isolate the protein and provide steric hindrance that mechanically refolds the protein. The groEL ring closes to isolate the protein and decode the information necessary to achieve the correct three-dimensional structure. None of the above
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