Which of the following statements best describes the appearance of amyloid plaques and neurofibrillary tangles in Alzheimer's Disease?
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Amyloid plaques do first appear in neocortical structures spreading to basal ganglia structures, while neurofibrillary tangles are first found in locus coeruleus spreading to the neocortex. |
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Amyloid plaques and neurofibrillary tangles do first appear in basal ganglia structures and then spread progressively to neocortical structures. |
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Amyloid plaques and neurofibrillary tangles are evenly spread throughout basal ganglia, diencephalic and neocortical structures. |
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Amyloid plaques and neurofibrillary tangles do first appear in neocortical structures and then spread progressively to basal ganglia structures. |
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