Which of the following statements about enzyme regulation is incorrect? Feedback inhibition is a mode of enzyme regulation employing negative allostery, where the final product of a pathway inhibits the first step of the same pathway The differential K and Vmax of hexokinase isoforms between the liver and muscle allows the tuning of enzyme activity to different substrate concentrations and overall tissue function The covalent modification of enzymes is a mechanism of regulation requiring kinase activity to install the phosphate, but where dephosphorylation can't occur spontaneously Proteolytic activation of enzymes converts a zymogen to an active enzyme by removal of peptide components and/or rearrangement of the protein backbone. All answers are correct

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