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Which of the following statements about enzyme regulation is incorrect? Feedback inhibition is a mode of enzyme regulation employing negative allostery, where the final product of a pathway inhibits the first step of the same pathway The differential K and Vmax of hexokinase isoforms between the liver and muscle allows the tuning of enzyme activity to different substrate concentrations and overall tissue function The covalent modification of enzymes is a mechanism of regulation requiring kinase activity to install the phosphate, but where dephosphorylation can't occur spontaneously Proteolytic activation of enzymes converts a zymogen to an active enzyme by removal of peptide components and/or rearrangement of the protein backbone. All answers are correct

Which of the following statements about enzyme regulation is incorrect? Feedback inhibition is a mode of enzyme regulation employing negative allostery, where the final product of a pathway inhibits the first step of the same pathway The differential K and Vmax of hexokinase isoforms between the liver and muscle allows the tuning of enzyme activity to different substrate concentrations and overall tissue function The covalent modification of enzymes is a mechanism of regulation requiring kinase activity to install the phosphate, but where dephosphorylation can't occur spontaneously Proteolytic activation of enzymes converts a zymogen to an active enzyme by removal of peptide components and/or rearrangement of the protein backbone. All answers are correct

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Which of the following statements about enzyme regulation is incorrect? Feedback inhibition is a mode of enzyme regulation employing negative allostery, where the final product of a pathway inhibits the first step of the same pathway The differential KM and Vmax of hexokinase isoforms between the liver and muscle allows the tuning of enzyme activity to different substrate concentrations and overall tissue function The covalent modification of enzymes is a mechanism of regulation requiring kinase activity to install the phosphate, but where dephosphorylation can't occur spontaneously Proteolytic activation of enzymes converts a zymogen to an active enzyme by removal of peptide components and/or rearrangement of the protein backbone. All answers are correct
Transcribed Image Text:Which of the following statements about enzyme regulation is incorrect? Feedback inhibition is a mode of enzyme regulation employing negative allostery, where the final product of a pathway inhibits the first step of the same pathway The differential KM and Vmax of hexokinase isoforms between the liver and muscle allows the tuning of enzyme activity to different substrate concentrations and overall tissue function The covalent modification of enzymes is a mechanism of regulation requiring kinase activity to install the phosphate, but where dephosphorylation can't occur spontaneously Proteolytic activation of enzymes converts a zymogen to an active enzyme by removal of peptide components and/or rearrangement of the protein backbone. All answers are correct
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