Which of the following reagent(s) would be considered a nucleophilic acid? Choose all that apply. HBr HI H2SO4 HCI QUESTION 10 Use the reaction shown below to answer questions 10-11. H2SO41 heat OH Based on the properties of the reagents, what will be the dominant mechanism in the reaction? SN2 ○ SN1 ○ E1 E2 QUESTION 11 What will be the major organic product formed from the reaction shown in the previous problem? A) B) OSO3H C) D) 4 OSO3 A B
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
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