Which of the following reactions correspond to the decarboxylation step during ketone body formation?
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Q: Consider docosanoic acid, C2,H43CO,H. a. Label the a and ß carbons. b. Draw the acyl COA derived…
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A:
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Which of the following reactions correspond to the decarboxylation step during
A. |
2 acetyl-CoA → acetoacetyl-CoA |
|
B. |
ß-hydroxybutarate → acetoacetate |
|
C. |
Acetoacetate → acetone |
|
D. |
HMG-CoA → mevalonate |
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- Which of the following are the precursors in synthesizing myristic acid? a. 7 malonyl-CoA b. 3 acetyl-CoA, 4 malonyl-CoA c. 1 acetyl-CoA, 6 malonyl-CoA d. 7 acetyl-CoAWhich one of the following will function to inhibit CPT1? A.palmitoyl-CoA B.citrate C propionyl-CoA D.acetyl-CoA E malonyl-CoAThe sources of the three (3) carbons in malonyl-Coa is/are: a. 1 C from C02 and 2 C from acetyl-CoA b. 1 C from HCO3- and 2 C from acetyl-CoA c. 1 C from biotin and 2 C from acetyl-CoA d. All three C from acetyl-CoA
- Order the steps that results in a triacylglycerol containing two palmitic acids and one stearic acid. a. Diacylglycerol reacts with an fatty-acyl-CoA b. Phosphate is remove from phosphatidic acid to form diacylglycerol c. Two of the fatty acyl-CoAs react with glycerol-3-phosphate d. An elongase produce stearic acid e. Stearoyl-CoA is synthesized…A patient who has been drinking large amounts of alcohol for long periods of time shows thefollowing symptoms: apathy, loss of memory, and a rhythmical to-and-fro motion of the eyeballs.Which of the following reactions are most likely to be affected in the patient? A. Conversation of pyruvate to acetyl-CoA B. Conversation of a-ketoglutarate to succinyl-CoA C. Both A and B D. Neither A nor BThe following reaction, the last reaction in beta-oxidation, is an example of a: Enzyme Enzyme-H S-CoA S-COA H2C H3C CoA s–CoA C H2 CH2 R S-COA S-COA S-COA O A. Nucleophilic acyl substitution O B. Electrophilic addition OC. Nucleophilic addition D. Aldol condensation O E. Hydrohalogenation
- Acetyl-CoA carboxylase is inhibited by A. biotin B. citrate C. acetyl-CoA D. palmitateDefine the following terms: a. thiolytic cleavage b. ketogenesis c. ketone bodies d. α-oxidation e. ACCalpha-ketoglutarate dehydrogenase will do which of the following: Select one: a. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide b. Succinate is oxidized to become fumarate forming FADH2 c. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SH d. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) e. Malate is oxidized to become oxaloacetate forming NADH f. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH g. Citrate is rearranged to become Isocitrate h. Fumarate is combined with water to become Malate i. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH
- Match the fatty acid catabolism reaction to the enzyme responsible. Not all the reactions have to be selected, and a reaction may be used more than once. AcylCoA dehydrogenase A. Hydrates double bond between C2 and C3 - Enoyl-CoA hydratase B. Attach acyl-CoA to carnitine - B-Hydroxyacyl-CoA dehydrogenase C Catalyze double-bond relocation Thiolase D. Reduces hydroxyl group to ketone A3.A2 enoyl isomerase E. Oxidizes hydroxyl group to ketone v Methylmalonyl-COA mutase F. Catalyzes intramolecular arrangement G. Hydrates double bond between C2 and C3 - Fatty acyl-CoA synthetase v Carnitine acyltransferase H. Reduces acyl-COA L Activates a fatty acid for b-oxidation J. Generate acyl-CoA and acetyl-CoA K. Removes acyl from camitine L. Oxidizes acyl-CoAWhich is co-produced from the conversion of fatty hydroxyacyl CoA to ketoacyl CoA? a. NADH b. FADH2 c. Acetyl COA d. ATP Transamination of glutamate will yield a. asparagine b. glutamine c. Succinyl CoA d. a-ketoglutarate The following amino acids are both glucogenic and ketogenic EXCEPT a. Isoleucine b. Tryptophan c. Leucine d. Tyrosine Which ofthe following is the precursor of fatty acid synthesis? а. Рyruvate b. Malonyl CoA c. Acetyl CoA d. Oxaloacetate • Carboxylation of acetyl CoA to produce malonyl CoA is catalyzed by a. Malonyl CoA carboxylase b. Pyruvate carboxylas c. Pyruvatew dehydrogenase d. Acetyl Co carboxylaseConsider the docosanoic acid, C21H43CO2H a. Label the a and B carbons b. Draw the acyl CoA derived from this fatty acid c. How many acetyl CoA molecules are formed by complete B-oxidation? d. How many cycles of B-oxidation are needed for complete oxidation? e. How many molecules of ATP are formed from the complete catabolism of this fatty acid?