Which of the following is favorable in a randomized controlled trial? OA. Use of competing interventions within a trial OB. Performing ad hoc analyses to support desired findings OC. Assessment of outcomes by various manners for different interventions D. Statistical power of at least 80%

MATLAB: An Introduction with Applications
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**Randomized Controlled Trials**

A randomized controlled trial (RCT) is a powerful research method used to assess the effectiveness of interventions. In designing and analyzing RCTs, several factors contribute to the validity and reliability of the results. 

### Favorable Practices in RCTs

Consider the following factors to determine which is favorable in a randomized controlled trial:

- **A. Use of competing interventions within a trial:** Introducing multiple interventions within the same trial for comparison.
  
- **B. Performing ad hoc analyses to support desired findings:** Conducting non-preplanned analyses to achieve specific outcomes, which can introduce bias.
  
- **C. Assessment of outcomes by various manners for different interventions:** Evaluating results through diverse methods for each intervention can help ensure comprehensive understanding, though consistency is crucial for validity.
  
- **D. Statistical power of at least 80%:** Ensuring adequate statistical power increases the likelihood of detecting a true effect when it exists, thus enhancing the credibility of the trial's results.

**Preferred Practice:**
- **D. Statistical power of at least 80%** is generally considered favorable as it indicates a high probability of correctly rejecting a false null hypothesis, thereby strengthening the findings of the trial.
Transcribed Image Text:**Randomized Controlled Trials** A randomized controlled trial (RCT) is a powerful research method used to assess the effectiveness of interventions. In designing and analyzing RCTs, several factors contribute to the validity and reliability of the results. ### Favorable Practices in RCTs Consider the following factors to determine which is favorable in a randomized controlled trial: - **A. Use of competing interventions within a trial:** Introducing multiple interventions within the same trial for comparison. - **B. Performing ad hoc analyses to support desired findings:** Conducting non-preplanned analyses to achieve specific outcomes, which can introduce bias. - **C. Assessment of outcomes by various manners for different interventions:** Evaluating results through diverse methods for each intervention can help ensure comprehensive understanding, though consistency is crucial for validity. - **D. Statistical power of at least 80%:** Ensuring adequate statistical power increases the likelihood of detecting a true effect when it exists, thus enhancing the credibility of the trial's results. **Preferred Practice:** - **D. Statistical power of at least 80%** is generally considered favorable as it indicates a high probability of correctly rejecting a false null hypothesis, thereby strengthening the findings of the trial.
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