Which of the following describes sequencing by synthesis? A. Large sections of DNA are inserted into a plasmid. B. DNA sequence is recorded as the complementary strand is built. C. Many copies of the DNA are made, each terminating at a specific nucleotide. D. A DNA strand is forced through a pore and its sequence synthesized as it passes through.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Which of the following describes sequencing by synthesis?

A. Large sections of DNA are inserted into a plasmid.
B. DNA sequence is recorded as the complementary strand is built.
C. Many copies of the DNA are made, each terminating at a specific nucleotide.
D. A DNA strand is forced through a pore and its sequence synthesized as it passes through.
Expert Solution
Introduction:

Sequencing of DNA means, determining the exact order in which the 4 nucleotides, viz. A, T, G, and C make the particular DNA segment. DNA sequencing has many advantages. It not only reveals the kind of information carried by that segment of DNA but helps in diagnosing several medical conditions and also is helpful in procuring individual-specific pharmacological treatments that work only for that individual.

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