When the molecule reacting with the electrophile is a strong nucleophile and a strong base, the substitution reaction is favoured when There is the least amount of crowding (steric hindrance) around the alpha carbon There is the most amount of crowding (steric hindrance) around the alpha carbon The leaving group is a strong base
When the molecule reacting with the electrophile is a strong nucleophile and a strong base, the substitution reaction is favoured when There is the least amount of crowding (steric hindrance) around the alpha carbon There is the most amount of crowding (steric hindrance) around the alpha carbon The leaving group is a strong base
Chemistry
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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:When the molecule reacting with the electrophile is a strong nucleophile and a
strong base, the substitution reaction is favoured when
There is the least amount of crowding (steric hindrance) around the alpha carbon
There is the most amount of crowding (steric hindrance) around the alpha carbon
The leaving group is a strong base
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