When is it safe to assume that the change from initial concentration (+/- x) is small enough to be negligible/ignore when doing equilibrium calculations for weak acids and bases?

Pushing Electrons
4th Edition
ISBN:9781133951889
Author:Weeks, Daniel P.
Publisher:Weeks, Daniel P.
Chapter3: Mechanisms
Section: Chapter Questions
Problem 31EQ: The reaction just described is reversible. Deprotonation of the conjugate acid of an organic base by...
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When is it safe to assume that the change from initial concentration (+/- x) is small enough to be negligible/ignore when doing equilibrium calculations for weak acids and bases? Be specific!

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