Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question
whats the order of atherogenesis process match each step in order 1-21

Transcribed Image Text:monocyte PSGL-1 binds to P-selectin
macrophage release of PDGF and FGF
macrophages become foam cells
LDL is converted into oxLDL
platelets stick to the atheroma
calcification of the atheroma and hardening of the plaque
smooth muscle cell entry into the intima
atheroma formation
monocyte diapedesis
collagen eposure on the atheroma
foam cell necrosis and release of lipid remnants
endothelial/smooth muscle cell cap rupture
LDL leakage into the intima
a thrombus forms
prothrombin becomes thrombin
endothelial VCAM1 binding to monocyte alpha4beta1
MCP-1 binding to monocytes
monocyte adhesion to the endothelium
endothelial damage
fibrinogen becomes fibrin
monocyte rolling along the endothelium
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