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What would be the consequence of the mismatch repair system lacking the methylating enzyme?

What would be the consequence of the mismatch repair system lacking the methylating enzyme?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Question 10:** What would be the consequence of the mismatch repair system lacking the methylating enzyme? This question is aimed at exploring the implications of a mismatch repair system that is deficient in the enzyme responsible for methylation. The mismatch repair system is crucial for maintaining DNA integrity by correcting errors that occur during DNA replication. The methylating enzyme plays a significant role in marking the template strand, allowing the system to distinguish between the old and newly synthesized DNA strands. A deficiency in this enzyme could impair the system's ability to accurately repair mismatches, potentially leading to an increase in mutations and genomic instability.
Transcribed Image Text:**Question 10:** What would be the consequence of the mismatch repair system lacking the methylating enzyme? This question is aimed at exploring the implications of a mismatch repair system that is deficient in the enzyme responsible for methylation. The mismatch repair system is crucial for maintaining DNA integrity by correcting errors that occur during DNA replication. The methylating enzyme plays a significant role in marking the template strand, allowing the system to distinguish between the old and newly synthesized DNA strands. A deficiency in this enzyme could impair the system's ability to accurately repair mismatches, potentially leading to an increase in mutations and genomic instability.
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