What were three key differences between the indigenous communities of North America and the European colonists who arrived in the 15th and 16th centuries and how were these differences amplified by continued European settlement and how did they contribute to the increased hostile relationship between the two groups?

What were three key differences between the indigenous communities of North America and the European colonists who arrived in the 15th and 16th centuries and how were these differences amplified by continued European settlement and how did they contribute to the increased hostile relationship between the two groups?